EC Number   |
Protein Variants |
Reference |
|---|
    1.8.1.9 | A164G/R183F |
the mutant shows reduced activity but is still able to dimerize though with an increase in intermediary forms |
700310 |
| 1.8.1.9 | A164G/V182E |
the mutant shows increased activity compared to the wild type enzyme |
700310 |
| 1.8.1.9 | A164G/V182E/R183F |
the mutant shows reduced activity compared to the wild type enzyme but is still able to dimerize though with an increase in intermediary forms |
700310 |
| 1.8.1.9 | C120A/C220A |
site-directed mutagenesis, the mutant retains NADPH oxidase activity, but with reduced activity compared to the wild-type enzyme |
765746 |
| 1.8.1.9 | C122A |
site-directed mutagenesis, the mutant retains NADPH oxidase activity, but with reduced activity compared to the wild-type enzyme |
-, 765746 |
| 1.8.1.9 | C135S |
exchange of 1 cysteine in the active center disulfide, 1 cysteine at position 138 is remaining |
394946 |
| 1.8.1.9 | C135S |
fluorescence spectroscopic investigation of the interaction with the flavin group |
394946 |
| 1.8.1.9 | C135S/C32S |
via the active disulfide centers a subunit complex of tightly bound enzyme, C135 and C138, and thioredoxin, C32 and C35, is formed, exchange of one cysteine for one serine in each protein by site-directed mutagenesis, conformation analysis |
394935 |
| 1.8.1.9 | C135S/C35S |
fluorescence spectroscopic investigation of the interaction with the flavin group |
394946 |
| 1.8.1.9 | C136S |
site-directed mutagenesis, reduced activity |
394910 |
