EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.22.B26 | Atherosclerosis |
27525442 |
Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
2
2
0 |
| 3.4.22.B26 | Bone Resorption |
20814968 |
Calpain 6, a target molecule of glucocorticoids, regulates osteoclastic bone resorption via cytoskeletal organization and microtubule acetylation. |
therapeutic application
unassigned |
1
0 |
| 3.4.22.B26 | calpain 6 deficiency |
23935533 |
Calpain-6 deficiency promotes skeletal muscle development and regeneration. |
causal interaction
unassigned |
4
0 |
| 3.4.22.B26 | calpain 6 deficiency |
27525442 |
Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
2
2
0 |
| 3.4.22.B26 | calpain 6 deficiency |
31619317 |
Deficiency of calpain-6 inhibits primary ciliogenesis. |
causal interaction
unassigned |
4
0 |
| 3.4.22.B26 | Carcinogenesis |
18657900 |
Calpain 6 supports tumorigenesis by inhibiting apoptosis and facilitating angiogenesis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
3 |
| 3.4.22.B26 | Carcinogenesis |
27987347 |
Integrated analysis reveals candidate mRNA and their potential roles in uterine leiomyomas. |
causal interaction
unassigned |
2
0 |
| 3.4.22.B26 | Carcinogenesis |
28454386 |
Decreased calpain 6 expression is associated with tumorigenesis and poor prognosis in HNSCC. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
2
0 |
| 3.4.22.B26 | Carcinogenesis |
33000175 |
CAPN6 in disease: An emerging therapeutic target (Review). |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.4.22.B26 | Carcinoma |
28454386 |
Decreased calpain 6 expression is associated with tumorigenesis and poor prognosis in HNSCC. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
2
0 |
