EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   2.7.11.1 | 0.000001 |
- |
MLN8054 |
wild type Aurora A kinase |
709439 |
| 2.7.11.1 | 0.0000018 |
- |
staurosporine |
mutant enzyme G2019S |
708481 |
| 2.7.11.1 | 0.000002 |
- |
(S)-2-(2-aminopyrimidiny-4-yl)-7-(2-fluoroethyl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridinione |
- |
708371 |
| 2.7.11.1 | 0.000002 |
- |
staurosporine |
wild type enzyme |
708481 |
| 2.7.11.1 | 0.0000028 |
- |
K252a |
mutant enzyme G2019S |
708481 |
| 2.7.11.1 | 0.000003 |
- |
2-phenyl-5-(pyridin-4-yl)-1H-pyrrole-3-carboxamide |
- |
708371 |
| 2.7.11.1 | 0.0000036 |
- |
K252a |
wild type enzyme |
708481 |
| 2.7.11.1 | 0.000005 |
- |
6-(3-chlorophenyl)-4-(1H-indazol-5-yl)pyrimidin-2(1H)-one |
- |
708371 |
| 2.7.11.1 | 0.000006 |
- |
2-chloro-N-(4-(5-fluoro-2-(4-hydroxyphenylamino)pyrimidin-4-ylamino)phenyl)benzamide |
wild type Aurora A kinase |
709439 |
| 2.7.11.1 | 0.000007 |
- |
2-(2-aminopyrimidin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one |
- |
708371 |
