EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
    1.5.1.3 | -999 |
- |
(-)-epicatechin |
value above 2.5 mM, pH 6, 25°C |
765650 |
| 1.5.1.3 | -999 |
- |
(-)-epicatechin gallate |
value above 1 mM, pH 6, 25°C |
765650 |
| 1.5.1.3 | -999 |
- |
more |
folate, IC50 value around 0.02 mM, epigallocatechin-3-gallate, IC50 value around 0.1 mM, respectively |
686360 |
| 1.5.1.3 | 0.0000000088 |
- |
methotrexate |
pH 7.0, 37°C |
705044 |
| 1.5.1.3 | 0.00000001 |
- |
trimethoprim |
pH 7.0, 37°C |
705044 |
| 1.5.1.3 | 0.000000011 |
- |
1,6-bis-(4-fluoro-phenyl)-[1,3,5]triazine-2,4-diamine |
IC50: 0.011 nM, 0.03 mM 7,8-dihydrofolate |
654970 |
| 1.5.1.3 | 0.000000011 |
- |
7-methyl-5,6,7,8-tetrahydro-quinazoline-2,4-diamine |
IC50: 0.011 nM, 0.03 mM 7,8-dihydrofolate |
654970 |
| 1.5.1.3 | 0.000000019 |
- |
N-(4-[(2-amino-6-ethyl-4-oxo-3,4-dihydrothieno[2,3-d ]pyrimidin-5-yl)thio]benzoyl)-L-glutamic acid |
pH 7.0, 37°C |
705044 |
| 1.5.1.3 | 0.00000002 |
- |
methotrexate |
pH 7.0, 37°C |
705044 |
| 1.5.1.3 | 0.00000002 |
- |
N-(4-[(2-amino-6-methyl-4-oxo-3,4-dihydrothieno[2,3-d ]pyrimidin-5-yl)thio]benzoyl)-L-glutamic acid |
pH 7.0, 37°C |
705044 |
