EC Number   |
General Information |
Reference |
|---|
    5.3.1.9 | malfunction |
deficiency of the enzymatic activity in red blood cells causes nonspherocytic hemolytic anemia |
702456 |
| 5.3.1.9 | malfunction |
enzyme deficiency leads to nonspherocytic hemolytic anemia |
726971 |
| 5.3.1.9 | malfunction |
neuromuscular symptoms are associated with inherited GPI deficiency |
704708 |
| 5.3.1.9 | malfunction |
PGI/AMF is correlated with breast cancer and poor prognosis in breast cancer. Inhibition of PGI/AMF expression triggers mesenchymal-to-epithelial transition in aggressive mesenchymal-type breast cancer MD-MB-231 cells |
703022 |
| 5.3.1.9 | metabolism |
GPI plays an important role in glycolysis |
-, 705640 |
| 5.3.1.9 | metabolism |
key enzyme in the AMF signaling pathway, overview |
704574 |
| 5.3.1.9 | metabolism |
PGI is a key enzyme in glycolysis and glycogenesis catalyzing the second step of glycolysis |
701552 |
| 5.3.1.9 | metabolism |
PGI is the second enzyme of glycolysis |
-, 706649 |
| 5.3.1.9 | metabolism |
phosphoglucose isomerase is a key enzyme in the glycolysis and glycogenesis pathways |
714592 |
| 5.3.1.9 | physiological function |
a leaky mutant expressing PGI1 at a level of 1.9% of the wild type, is able to synthesize the pigment melanin in the presence of 2% glucose. Capsule biosynthesis is remarkably reduced in the mutant, integrity of the cell wall and plasma membrane are impaired. The mutant exhibits hypersensitivity to osmotic stress generated by 2 M NaCl or 1 M KCl and fails to utilize mannose and fructose |
-, 747804 |
