EC Number   |
Expression |
Reference |
|---|
   3.4.24.80 | down |
cyclosporine A inhibits expression of membrane-type I MMP in gingiva |
709668 |
| 3.4.24.80 | down |
cyclosporine A inhibits expression of membrane-type I MMP, but not of TIMP-2, in gingiva. Transcription of MMP-2 is unaffected, but translation is inhibited |
709668 |
| 3.4.24.80 | down |
endothelin-1 (ET-1) downregulates matrix metalloproteinase 14 expression in human first trimester trophoblasts via endothelin receptor type B (ETRB). ET-1 downregulates MMP14 mRNA and protein levels. TNF-alpha enhances ET-1-mediated MMP14 downregulation in primary trophoblasts |
753776 |
| 3.4.24.80 | more |
MCF-7 cells are transfected with human CCN5 using a polyclonal anti-VTSP antibody detected only full length CCN5. CCN5 cleavage occurs upon coexpression of MMP14 with CCN5 in the MCF-7 cells resulting in the loss of the VTSP epitope in the medium. Cleavage of full-length CCN5 in the CHO-K1-conditioned medium upon addition of recombinant MMP14 or MMP2 |
754591 |
| 3.4.24.80 | up |
collagen upregulates both MT1-MMP gene and functions in various cell types |
754158 |
| 3.4.24.80 | up |
in patients with tuberculosis, induced sputum enzyme mRNA levels are increased 5.1fold compared with matched controls. Mycobacterium tuberculosis infection of primary human monocytes increases enzyme surface expression 31.7fold and gene expression 24.5fold |
734409 |
| 3.4.24.80 | up |
interleukin-6 enhances matrix metalloproteinase-14 expression through activator protein-1, AP-1, and via the induced RAF-mitogen-activated protein kinase kinase-extracellular signal-regulated kinase 1/2-activator protein-1 pathway, overview |
708193 |
| 3.4.24.80 | up |
MMP-8 is upregulated after stroke in brain in the infarcted tissue compared to healthy control areas, overview |
709700 |
| 3.4.24.80 | up |
Snail increases the expression of membrane type 1-matrix metalloproteinase through activation of ERK-MAPK signaling |
719913 |
| 3.4.24.80 | up |
the enzyme is induced by collagen-gel culture or con-canavalin A treatment |
733605 |
