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Literature summary for 3.4.24.80 extracted from
- Pancreatic cancer cells respond to type I collagen by inducing Snail expression to promote membrane type 1 matrix metalloproteinase-dependent collagen invasion (2011), J. Biol. Chem., 286, 10495-10504.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| GM6001 | - |
Homo sapiens |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 66000 | - |
x * 66000, SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pancreatic ductal adenocarcinoma cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| type 1 collagen + H2O | - |
Homo sapiens | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 66000, SDS-PAGE | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| membrane type 1 matrix metalloproteinase | - |
Homo sapiens |
| MT1-MMP | - |
Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | Snail increases the expression of membrane type 1-matrix metalloproteinase through activation of ERK-MAPK signaling | up |
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Release 2023.1 (January 2023)
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