EC Number   |
Expression |
Reference |
|---|
    3.1.3.4 | down |
downregulation of LPIN-1 by RNAi |
709219 |
| 3.1.3.4 | down |
hepatic lipin-1 expression is selectively repressed by insulin |
714316 |
| 3.1.3.4 | down |
homozygous T-DNA-tagged mutants of PAH1 and PAH2 do not express their respective full-length mRNAs |
710418 |
| 3.1.3.4 | down |
in polycystic ovary syndrome patients, lipin 1beta expression in subcutaneous and visceral adipose tissue depots is lower than in controls. In polycystic ovary syndrome patients, visceral adipose lipin 1beta expression correlates negatively with homeostasis model assessment-insulin resistance, body mass index and waist circumference. Subcutaneous lipin 1beta expression in polycystic ovary syndrome patients correlates negatively with body mass index, waist circumference and plasma triglycerides |
708377 |
| 3.1.3.4 | down |
in the 3T3-L1 cell line, lipin-2 protein levels decline dramatically as adipocyte differentiation proceeds to become virtually undetectable in mature adipocytes, when lipin-1 is expressed at high levels |
707555 |
| 3.1.3.4 | down |
lipin 1 knockdown by shRNA, decline in lipin 1 expression with increasing obesity in ob/ob mice |
709945 |
| 3.1.3.4 | down |
LPIN1 mRNA levels decrease significantly after transfection with LPIN1 siRNA. LPIN1 mRNA levels are reduced to ca. 0.6fold after transfection with SREBP-1 siRNA |
709037 |
| 3.1.3.4 | down |
LPP2 expression is down-regulated by abscisic acid (0.01 mM) |
716574 |
| 3.1.3.4 | down |
LPP3 expression is negatively correlated with vascular endothelial growth factor expression |
750250 |
| 3.1.3.4 | down |
RNAi against lipin 2 markedly reduces PAP-1 activity in hepatocytes from both wild-type and fld mice and suppresses triglyceride synthesis under conditions of high fatty acid availability |
709098 |
