EC Number   |
Application |
Reference |
|---|
    3.5.1.14 | analysis |
enzyme widely used as reagent to resolve amino acid racemates |
288864 |
| 3.5.1.14 | diagnostics |
the enzyme is an important biomarker with potential prognostic utility in patients with delayed graft function following renal transplantation. The possibility of using 4-[(E)-2-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]ethenyl]phenyl prop-2-enoate for quantification of aminoacylase-1 in blood serum samples is explored. Nontoxic nature and cell membrane permeability are key features of this probe and are ideally suited for imaging intracellular Cys in normal and cancerous cell lines .CA can be used for selective detection of Cys in the presence of the competing biothiols, cations, and anions of biological relevance. This reagent is successfully utilized for monitoring the hydrolysis of an important commercial drug molecule N-acetyl-L-cysteine by an industrially and biologically important endogenous enzyme, aminoacylase-1 |
752480 |
| 3.5.1.14 | medicine |
N-acetyl-L-cysteine used for drugs against lung disorders and HIV infections, test of potential antitumor agents |
288871 |
| 3.5.1.14 | medicine |
preparation of commercially important amino acids as components for semisynthetic penicillins and cephalosporins |
288858 |
| 3.5.1.14 | medicine |
the enzyme is an important biomarker with potential prognostic utility in patients with delayed graft function following renal transplantation |
752480 |
| 3.5.1.14 | synthesis |
- |
-, 288863, 288866, 288867, 288872, 288873 |
| 3.5.1.14 | synthesis |
aminoacylase-catalyzed enantioselective synthesis of aromatic beta-amino acids |
670454 |
| 3.5.1.14 | synthesis |
because of its thermostability, the enzyme is expected to be useful for the production of L-amino acid derivatives from racemates at temperatures over 90°C |
-, 721329 |
| 3.5.1.14 | synthesis |
biocatalytic production of optically active amino acids and their derivatives, which are broadly used as physiologically active compounds, chiral auxiliaries or synthons and as intermediates in pharmaceutical, food and agrochemistry |
670918 |
| 3.5.1.14 | synthesis |
enzyme used for production of L-amino acids |
288863 |
