EC Number   |
Application |
Reference |
|---|
    1.8.1.9 | agriculture |
under cadmium stress conditions, NTR activity and thioredoxin h3 and thioredoxin h4 expression are stimulated |
743162 |
| 1.8.1.9 | analysis |
thioredoxin reductase-1 may be an early indicator of acute exposure to low lead doses |
684809 |
| 1.8.1.9 | medicine |
both pharmacological and toxicological effects of anti-cancer drug cisplatin involve TrxR inactivation, and the large enhancement on cisplatin cure rate in H22 ascites model by using amifostine is, at least in part, ascribed to its selective modulation on TrxR |
685928 |
| 1.8.1.9 | medicine |
development of novel anticancer agents |
675915 |
| 1.8.1.9 | medicine |
inhibition of thioredoxin reductase represents a potential target in pancreatic cancer and provides a biomarker of effect of lead indolequinones in this type of cancer |
713067 |
| 1.8.1.9 | medicine |
potential drug target for malaria chemotherapy |
672588 |
| 1.8.1.9 | medicine |
target for a chemotherapeutic intervention of malaria |
394938 |
| 1.8.1.9 | medicine |
target for immunostimulating effect of 1-chloro-2,4-dinitrobenzene as agent in AIDS treatment |
394941 |
| 1.8.1.9 | medicine |
thioredoxin reductase is a antimalarial drug target |
699879 |
| 1.8.1.9 | medicine |
TR1 acts largely as a pro-cancer protein and it is a primary target in cancer therapy |
689708 |
