EC Number |
Metals/Ions |
Reference |
---|
3.5.1.15 | Ca2+ |
stimulates activity 20-40% |
209005 |
3.5.1.15 | Mg2+ |
stimulates activity 20-40% |
209005 |
3.5.1.15 | Mn2+ |
stimulates activity 20-40%, above 0.1 mM inhibition |
209005 |
3.5.1.15 | Zn2+ |
contains zinc |
720276 |
3.5.1.15 | Zn2+ |
essential for activity |
679264 |
3.5.1.15 | Zn2+ |
metallopeptidase, the enzyme contains the conserved H21XXE24(91aa)H116 motif, ligand binding by His21, Glu24, and His116, molecular modeling |
668640 |
3.5.1.15 | Zn2+ |
necessary for activity |
682568 |
3.5.1.15 | Zn2+ |
necessary for activity, coordinated by residues His-21, Glu-24, and His-116 and a phosphate |
682568 |
3.5.1.15 | Zn2+ |
one zinc ion per monomer |
678338 |
3.5.1.15 | Zn2+ |
required for activity, spectroscopical determination of metal content, the enzyme contains about 1 Zn2+ per enzyme subunit |
667727 |