EC Number   |
Activating Compound |
Reference |
|---|
   2.7.11.16 | arrestins |
arrestins modulate the enzyme activity having a regulatory role, regulation of arrestins, overview |
662911 |
| 2.7.11.16 | isoproterenol |
stimulates the phosphorylation activity of GRK5 by10-15fold at 0.001 mM |
685121 |
| 2.7.11.16 | methacholine |
stimulation of M3 muscarinic acetylcholine receptor phosphorylation is reversible by atropine |
662912 |
| 2.7.11.16 | more |
autophosphorylation of GRK5 is stimulated by phospholipids, such as phosphatidylinositol-4,5-bisphosphate |
662911 |
| 2.7.11.16 | more |
GRK6 activity on the M3 muscarinic acetylcholine receptor is not affected by phorbol-12,13-dibutyrate and Ro 31-8220 |
662912 |
| 2.7.11.16 | more |
no interaction with G protein Gbetagamma subunits by GRK4, which contains no N-terminal RGS domain |
662767 |
| 2.7.11.16 | more |
phosphorylation activates the enzyme |
672408 |
| 2.7.11.16 | phosphatidylinositol 4,5-bisphosphate |
activates the receptor phosphorylation activity of GRK5, but not its autophosphorylation or peptide phosphorylation activity |
661455 |
| 2.7.11.16 | Phospholipids |
activate GRK5 |
661455 |
