Ontology explorer

Gene ontology

Change ontology: Version 2014-12-22

Term or Synonym: use AND (NOT) or OR

Definition: use AND (NOT) or OR

Id:

restrict to BRENDA links:

Localization

Enzyme

Details for inositol-3-phosphate synthase activity

5.5.1.4

Gene ontology ID

GO:0004512

Definition

Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form

Synonyms

1. 1L-myo-inositol-1-phosphate lyase (isomerizing)
2. D-glucose 6-phosphate cycloaldolase activity
3. glucocycloaldolase activity
4. glucose 6-phosphate cyclase activity
5. glucose-6-phosphate inositol monophosphate cycloaldolase activity
6. inositol 1-phosphate synthatase activity
7. inositol 1-phosphate synthetase activity

References

1. EC 5.5.1.4
2. RHEA: 10716
3. KEGG REACTION: R07324
4. MetaCyc MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN
5. Reactome: R-HSA-1855178 "Glc6P is isomerised to I3P by ISYNA1 in the cytosol"

Legend

is an element of the parent element

is a part of the parent element

is related to the parent element

derives from the parent element

at least 1 tissue/ enzyme/ localization link in this branch

tissue/ enzyme/ localization link to BRENDA

Condensed Tree View

Gene ontology

molecular_function is a

catalytic activity is a

isomerase activity is a

intramolecular lyase activity is a

inositol-3-phosphate synthase activity is a

Tree view

Gene ontology

biological_process is a

cellular_component is a

molecular_function is a

binding

catalytic activity is a

catalytic activity, acting on a protein is a

catalytic activity, acting on DNA is a

catalytic activity, acting on RNA is a

cyclase activity is a

hydrolase activity is a

isomerase activity is a

(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity is a

4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity is a

cis-trans isomerase activity is a

dihydroneopterin triphosphate 2'-epimerase activity is a

eoxin A4 synthase activity is a

hepoxilin A3 synthase activity is a

hexulose-6-phosphate isomerase activity is a

intramolecular lyase activity is a

3-carboxy-cis,cis-muconate cycloisomerase activity is a

3-carboxymuconate cycloisomerase type II activity is a

alpha-pinene lyase activity is a

alpha-pinene-oxide decyclase activity is a

chalcone isomerase activity is a

chloromuconate cycloisomerase activity is a

copalyl diphosphate synthase activity is a

cycloeucalenol cycloisomerase activity is a

cyclopropanecarboxyl-CoA decyclase activity is a

dichloromuconate cycloisomerase activity is a

ent-copalyl diphosphate synthase activity is a

inositol-3-phosphate synthase activity is a

kolavenyl diphosphate synthase activity is a

muconate cycloisomerase activity is a

pinocarveol isomerase activity is a

syn-copalyl diphosphate synthase activity is a

tetrahydroxypteridine cycloisomerase activity is a

intramolecular oxidoreductase activity is a

intramolecular transferase activity is a

N-acylmannosamine-6-phosphate 2-epimerase activity is a

peroxynitrite isomerase activity is a

racemase and epimerase activity is a

sulfoquinovose isomerase activity is a

thiocyanate isomerase activity is a

ligase activity is a

lyase activity is a

peptidoglycan muralytic activity is a

transferase activity is a

molecular transducer activity is a

nutrient reservoir activity is a

protein tag is a

small molecule sensor activity is a

structural molecule activity is a

transcription regulator activity is a

transporter activity is a