Reference on EC 5.4.99.1 - methylaspartate mutase and Organism(s) Clostridium cochlearium and UniProt Accession P80078
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
topREF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bothe, H.; Darley, D.J.; Albracht, S.P.; Gerfen, G.J.; Golding, B.T.; Buckel, W.
Identification of the 4-glutamyl radical as an intermediate in the carbon skeleton rearrangement catalyzed by coenzyme B12-dependent glutamate mutase from Clostridium cochlearium
Biochemistry
37
4105-4113
1998
Clostridium cochlearium
Switzer, R.L.
Glutamate mutase
B12 (Dolphin, D. ed. ) Wiley, New York
2
289-305
1982
Clostridium cochlearium, Clostridium saccharobutyricum, Clostridium sp., Acetoanaerobium sticklandii, Clostridium tetani, Clostridium tetanomorphum, no activity in Acidaminococcus fermentans, no activity in Clostridium microsporum, no activity in Fusobacterium fusiforme, no activity in Fusobacterium nucleatum, no activity in Micrococcus aerogenes, Cereibacter sphaeroides, Rhodospirillum rubrum, Clostridium sp. SB4
-
Barker, H.A.
Coenzyme B12-dependent mutases causing carbon chain rearrangements
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
6
509-537
1972
Cereibacter sphaeroides, Clostridium cochlearium, Clostridium tetanomorphum, Rhodospirillum rubrum
-
Chen, H.P.; Marsh, E.N.G.
Adenosylcobalamin-dependent glutamate mutase: examination of substrate and coenzyme binding in an engineered fusion protein possessing simplified subunit structure and kinetic properties
Biochemistry
36
14939-14945
1997
Clostridium cochlearium
Buckel, W.; Golding, B.T.
Glutamate and 2-methyleneglutarate mutase: from microbial curiosities to paradigms for coenzyme B12-dependent enzymes
Chem. Soc. Rev.
25
329-337
1996
Clostridium cochlearium, Clostridium tetanomorphum
-
Leutbecher, U.; Bcher, R.; Linder, D.; Buckel, W.
Glutamate mutase from Clostridium cochlearium
Eur. J. Biochem.
205
759-765
1992
Clostridium cochlearium
Reitzer, R.; Krasser, M.; Jogl, G.; Buckel, W.; Bothe, H.; Kratky, C.
Crystallization and preliminary X-ray analysis of recombinant glutamate mutase and of the isolated component S from Clostridium cochlearium
Acta Crystallogr. Sect. D
54
1039-1042
1998
Clostridium cochlearium
Zelder, O.; Beatrix, B.; Leutbecher, U.; Buckel, W.
Characterization of the coenzyme-B12-dependent glutamate mutase from Clostridium cochlearium produced in Escherichia coli
Eur. J. Biochem.
226
577-585
1994
Clostridium cochlearium
Roymoulik, I.; Moon, N.; Dunham, W.R.; Ballou, D.P.; Marsh, E.N.
Rearrangement of L-2-hydroxyglutarate to L-threo-3-methylmalate catalyzed by adenosylcobalamin-dependent glutamate mutase
Biochemistry
39
10340-10346
2000
Clostridium cochlearium
Huhta, M.S.; Ciceri, D.; Golding, B.T.; Marsh, E.N.
A novel reaction between adenosylcobalamin and 2-methyleneglutarate catalyzed by glutamate mutase
Biochemistry
41
3200-3206
2002
Clostridium cochlearium
Xia, L.; Ballou, D.P.; Marsh, E.N.
Role of arg100 in the active site of adenosylcobalamin-dependent glutamate mutase
Biochemistry
43
3238-3245
2004
Clostridium cochlearium
Madhavapeddi, P.; Marsh, E.N.
The role of the active site glutamate in the rearrangement of glutamate to 3-methylaspartate catalyzed by adenosylcobalamin-dependent glutamate mutase
Chem. Biol.
8
1143-1149
2001
Clostridium cochlearium
Gruber, K.; Kratky, C.
Coenzyme B(12) dependent glutamate mutase
Curr. Opin. Chem. Biol.
6
598-603
2002
Clostridium cochlearium
Hoffmann, B.; Konrat, R.; Bothe, H.; Buckel, W.; Krautler, B.
Structure and dynamics of the B12-binding subunit of glutamate mutase from Clostridium cochlearium
Eur. J. Biochem.
263
178-188
1999
Clostridium cochlearium
Chih, H.W.; Marsh, E.N.G.
Mechanism of glutamate mutase: identification and kinetic competence of acrylate and glycyl radical as intermediates in the rearrangement of glutamate to methylaspartate
J. Am. Chem. Soc.
122
10732-10733
2000
Clostridium cochlearium
-
Roymoulik, I.; Chen, H.P.; Marsh, E.N.
The reaction of the substrate analog 2-ketoglutarate with adenosylcobalamin-dependent glutamate mutase
J. Biol. Chem.
274
11619-11622
1999
Clostridium cochlearium
Reitzer, R.; Gruber, K.; Jogl, G.; Wagner, U.G.; Bothe, H.; Buckel, W.; Kratky, C.
Glutamate mutase from Clostridium cochlearium: the structure of a coenzyme B12-dependent enzyme provides new mechanistic insights
Structure
7
891-902
1999
Clostridium cochlearium
Cheng, M.C.; Marsh, E.N.
Pre-steady-state measurement of intrinsic secondary tritium isotope effects associated with the homolysis of adenosylcobalamin and the formation of 5'-deoxyadensosine in glutamate mutase
Biochemistry
43
2155-2158
2004
Clostridium cochlearium
Brooks, A.J.; Fox, C.C.; Marsh, E.N.; Vlasie, M.; Banerjee, R.; Brunold, T.C.
Electronic structure studies of the adenosylcobalamin cofactor in glutamate mutase
Biochemistry
44
15167-15181
2005
Clostridium cochlearium
Cheng, M.C.; Marsh, E.N.
Isotope effects for deuterium transfer between substrate and coenzyme in adenosylcobalamin-dependent glutamate mutase
Biochemistry
44
2686-2691
2005
Clostridium cochlearium
Sension, R.J.; Cole, A.G.; Harris, A.D.; Fox, C.C.; Woodbury, N.W.; Lin, S.; Marsh, E.N.G.
Photolysis and recombination of adenosylcobalamin bound to glutamate mutase
J. Am. Chem. Soc.
126
1598-1599
2004
Clostridium cochlearium
Sension, R.J.; Harris, D.A.; Stickrath, A.; Cole, A.G.; Fox, C.C.; Marsh, E.N.G.
Time-resolved measurements of the photolysis and recombination of adenosylcobalamin bound to glutamate mutase
J. Phys. Chem. B
109
18146-18152
2005
Clostridium cochlearium
Patwardhan, A.; Marsh, E.N.
Changes in the free energy profile of glutamate mutase imparted by the mutation of an active site arginine residue to lysine
Arch. Biochem. Biophys.
461
194-199
2007
Clostridium cochlearium
Yoon, M.; Patwardhan, A.; Qiao, C.; Mansoorabadi, S.O.; Menefee, A.L.; Reed, G.H.; Marsh, E.N.
Reaction of adenosylcobalamin-dependent glutamate mutase with 2-thiolglutarate
Biochemistry
45
11650-11657
2006
Clostridium cochlearium
Cheng, M.C.; Marsh, E.N.
Evidence for coupled motion and hydrogen tunneling of the reaction catalyzed by glutamate mutase
Biochemistry
46
883-889
2007
Clostridium cochlearium
Sandala, G.M.; Smith, D.M.; Marsh, E.N.; Radom, L.
Toward an improved understanding of the glutamate mutase system
J. Am. Chem. Soc.
129
1623-1633
2007
Clostridium cochlearium
Kozlowski, P.M.; Kamachi, T.; Kumar, M.; Nakayama, T.; Yoshizawa, K.
Theoretical analysis of the diradical nature of adenosylcobalamin cofactor-tyrosine complex in B12-dependent mutases: inspiring PCET-driven enzymatic catalysis
J. Phys. Chem. B
114
5928-5939
2010
Clostridium cochlearium (P80077), Clostridium cochlearium (P80078)
Rommel, J.B.; Kaestner, J.
The fragmentation-recombination mechanism of the enzyme glutamate mutase studied by QM/MM simulations
J. Am. Chem. Soc.
133
10195-10203
2011
Clostridium cochlearium
