Information on EC 4.2.1.137 - sporulenol synthase

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The expected taxonomic range for this enzyme is: Bacillus

EC NUMBER
COMMENTARY hide
4.2.1.137
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RECOMMENDED NAME
GeneOntology No.
sporulenol synthase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
sporulenol = tetraprenyl-beta-curcumene + H2O
show the reaction diagram
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SYSTEMATIC NAME
IUBMB Comments
tetraprenyl-beta-curcumene-sporulenol cyclase
The reaction occurs in the reverse direction. Isolated from Bacillus subtilis. Similar sesquarterpenoids are present in a number of Bacillus species.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
gene sqhC
UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
metabolism
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
beta-hexaprene
?
show the reaction diagram
tetraprenyl-beta-curcumene + H2O
(2R,4aS,4bR,6aS,10aS,10bR,12aS)-1,4b,7,7,10a,12a-hexamethyl-2-[(3R)-3-(4-methylcyclohexa-1,4-dien-1-yl)butyl]octadecahydrochrysen-2-ol
show the reaction diagram
tetraprenyl-beta-curcumene + H2O
baciterpenol A
show the reaction diagram
additional information
?
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
tetraprenyl-beta-curcumene + H2O
(2R,4aS,4bR,6aS,10aS,10bR,12aS)-1,4b,7,7,10a,12a-hexamethyl-2-[(3R)-3-(4-methylcyclohexa-1,4-dien-1-yl)butyl]octadecahydrochrysen-2-ol
show the reaction diagram
tetraprenyl-beta-curcumene + H2O
baciterpenol A
show the reaction diagram
additional information
?
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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli
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gene sqhC, expression in Escherichia coli using pColdTF