Information on EC 4.1.1.86 - diaminobutyrate decarboxylase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Mark a special word or phrase in this record:
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)


The expected taxonomic range for this enzyme is: Gammaproteobacteria

EC NUMBER
COMMENTARY
4.1.1.86
-
RECOMMENDED NAME
GeneOntology No.
diaminobutyrate decarboxylase
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
L-2,4-diaminobutanoate = propane-1,3-diamine + CO2
show the reaction diagram
-
-
-
-
PATHWAY
KEGG Link
MetaCyc Link
Glycine, serine and threonine metabolism
-
Microbial metabolism in diverse environments
-
norspermidine biosynthesis
-
rhizobactin 1021 biosynthesis
-
SYSTEMATIC NAME
IUBMB Comments
L-2,4-diaminobutanoate carboxy-lyase (propane-1,3-diamine-forming)
A pyridoxal-phosphate protein that requires a divalent cation for activity [1]. N4-Acetyl-L-2,4-diaminobutanoate, 2,3-diaminopropanoate, ornithine and lysine are not substrates. Found in the proteobacteria Haemophilus influenzae and Acinetobacter baumannii. In the latter, this enzyme is cotranscribed with the dat gene that encodes EC 2.6.1.76, diaminobutyrate---2-oxoglutarate transaminase, which can supply the substrate for this enzyme.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
DABA aminotransferase/decarboxylase
-
-
DABA aminotransferase/decarboxylase
Vibrio cholerae El Tor
-
-
-
DABA AT
P56744
-
DABA AT/DC
-
-
DABA AT/DC
Vibrio cholerae El Tor
-
-
-
DABA DC
Q43908
-
DABA DC
Acinetobacter baumannii ATCC19606
-
;
-
DABA DC
Acinetobacter calcoaceticus ATCC23055
-
-
-
DABA DC
Q9S0P8
-
DABA DC
Serratia liquefaciens RM 2-Ia
-
-
-
DABA decarboxylase
-
-
DABA decarboxylase
Acinetobacter calcoaceticus ATCC23055
-
-
-
DABA decarboxylase
-
-
DABA decarboxylase
Listonella anguillarum NCMB6
-
-
-
DABA decarboxylase
-
-
DABA decarboxylase
Salinivibrio costicola NCMB701
-
-
-
DABA decarboxylase
-
-
DABA decarboxylase
Vibrio alginolyticus ATCC17749
-
-
-
DABA decarboxylase
-
-
DABA decarboxylase
Vibrio cholerae NCTC4716
-
-
-
DABA decarboxylase
-
-
DABA decarboxylase
Vibrio proteolyticus ATCC15338
-
-
-
DABA-DC
Enterobacter aerogenes NCTC 10006
-
-
-
L-2,4-diaminobutyrate aminotransferase/decarboxylase
-
-
L-2,4-diaminobutyrate aminotransferase/decarboxylase
Vibrio cholerae El Tor
-
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate decarboxylase
Q43908
-
L-2,4-diaminobutyrate decarboxylase
Acinetobacter baumannii ATCC19606
-
;
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate decarboxylase
Acinetobacter calcoaceticus ATCC23055
-
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate decarboxylase
Q9S0P8
-
L-2,4-diaminobutyrate decarboxylase
Serratia liquefaciens RM 2-Ia
-
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase
P56744
-
L-2,4-diaminobutyric acid decarboxylase
-
-
L-2,4-diaminobutyric acid decarboxylase
Enterobacter aerogenes NCTC 10006
-
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
L-2,4-diaminobutyric acid decarboxylase
Listonella anguillarum NCMB6
-
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
L-2,4-diaminobutyric acid decarboxylase
Salinivibrio costicola NCMB701
-
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
L-2,4-diaminobutyric acid decarboxylase
Vibrio alginolyticus ATCC17749
-
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
L-2,4-diaminobutyric acid decarboxylase
Vibrio cholerae NCTC4716
-
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
L-2,4-diaminobutyric acid decarboxylase
Vibrio proteolyticus ATCC15338
-
-
-
additional information
P56744
the enzyme belongs to the subgroup II of the aminotransferases
CAS REGISTRY NUMBER
COMMENTARY
110277-62-8
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
strain ATCC 19606, gene dat
SwissProt
Manually annotated by BRENDA team
strain ATCC19606
-
-
Manually annotated by BRENDA team
Acinetobacter baumannii ATCC19606
strain ATCC19606
-
-
Manually annotated by BRENDA team
N-terminal amino acid sequence; strain ATCC23055
-
-
Manually annotated by BRENDA team
strains ATCC23055 and IFO12552
-
-
Manually annotated by BRENDA team
Acinetobacter calcoaceticus ATCC23055
N-terminal amino acid sequence; strain ATCC23055
-
-
Manually annotated by BRENDA team
strain ATCC 8090
-
-
Manually annotated by BRENDA team
gene ddc
SwissProt
Manually annotated by BRENDA team
strain ATCC 13048
-
-
Manually annotated by BRENDA team
strain NCTC 10006
-
-
Manually annotated by BRENDA team
Enterobacter aerogenes NCTC 10006
strain NCTC 10006
-
-
Manually annotated by BRENDA team
strain ATCC 13047
-
-
Manually annotated by BRENDA team
strain ATCC 13182
-
-
Manually annotated by BRENDA team
strain ATCC 13882
-
-
Manually annotated by BRENDA team
strain NCMB6
-
-
Manually annotated by BRENDA team
Listonella anguillarum NCMB6
strain NCMB6
-
-
Manually annotated by BRENDA team
strain ATCC 27155
-
-
Manually annotated by BRENDA team
strain NCMB701
-
-
Manually annotated by BRENDA team
Salinivibrio costicola NCMB701
strain NCMB701
-
-
Manually annotated by BRENDA team
strain RM 2-Ia
-
-
Manually annotated by BRENDA team
Serratia liquefaciens RM 2-Ia
strain RM 2-Ia
-
-
Manually annotated by BRENDA team
strain ATCC 13880
-
-
Manually annotated by BRENDA team
Vibrio alginolyticus ATCC17749
ATCC17749
-
-
Manually annotated by BRENDA team
El Tor strain
-
-
Manually annotated by BRENDA team
strain NCTC4716, non-O1
-
-
Manually annotated by BRENDA team
Vibrio cholerae El Tor
El Tor strain
-
-
Manually annotated by BRENDA team
Vibrio cholerae NCTC4716
strain NCTC4716, non-O1
-
-
Manually annotated by BRENDA team
strain ATCC15338
-
-
Manually annotated by BRENDA team
Vibrio proteolyticus ATCC15338
strain ATCC15338
-
-
Manually annotated by BRENDA team
pI VALUE
pI VALUE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
5
-
-
isoelectric focusing
5.2
-
Q43908
amino acid sequence calculation
6.8
-
-
isoelectric focusing
ENGINEERING
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
K198R
Q9S0P8
site-directed mutagenesis, mutant shows 96% of the wild-type activity
K307R
Q9S0P8
site-directed mutagenesis, mutant is catalytically inactive and shows slightly reduced molecular weight compared to the wild-type enzyme due to lacking pyridoxal 5'-phosphate