Disease on EC 3.4.22.B72 - SENP3 peptidase
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Acute Lung Injury
SENP3 in monocytes/macrophages up-regulates tissue factor and mediates lipopolysaccharide-induced acute lung injury by enhancing JNK phosphorylation.
Brain Injuries
Expression and Cell Distribution of SENP3 in the Cerebral Cortex After Experimental Subarachnoid Hemorrhage in Rats: A Pilot Study.
Brain Injuries, Traumatic
Expression and Cell Distribution of SENP3 in Brain Tissue After Traumatic Brain Injury in Mice: A Pilot Study.
Breast Neoplasms
E2F1 sumoylation as a protective cellular mechanism in oxidative stress response.
Breast Neoplasms
SENP3 loss promotes M2 macrophage polarization and breast cancer progression.
Carcinogenesis
High SENP3 Expression Promotes Cell Migration, Invasion, and Proliferation by Modulating DNA Methylation of E-Cadherin in Osteosarcoma.
Carcinogenesis
Mitotic Phosphorylation of SENP3 Regulates De-SUMOylation of Chromosome-Associated Proteins and Chromosome Stability.
Carcinogenesis
Upregulation of SENP3/SMT3IP1 promotes epithelial ovarian cancer progression and forecasts poor prognosis.
Carcinoma
Nuclear Nrf2 Activity in Laryngeal Carcinoma is Regulated by SENP3 After Cisplatin-Induced Reactive Oxygen Species Stress.
Carcinoma
Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation.
Carcinoma, Hepatocellular
Combined identification of ARID1A, CSMD1, and SENP3 as effective prognostic biomarkers for hepatocellular carcinoma.
Carcinoma, Ovarian Epithelial
Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC).
Carcinoma, Ovarian Epithelial
Upregulation of SENP3/SMT3IP1 promotes epithelial ovarian cancer progression and forecasts poor prognosis.
Cardiovascular Diseases
The Critical Roles of the SUMO-Specific Protease SENP3 in Human Diseases and Clinical Implications.
Colonic Neoplasms
SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress.
Colorectal Neoplasms
SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function.
Epilepsy
SUMO proteases SENP3 and SENP5 spatiotemporally regulate the kinase activity of Aurora A.
Fatty Liver
SUMO-specific protease 3 is a key regulator for hepatic lipid metabolism in non-alcoholic fatty liver disease.
Head and Neck Neoplasms
SUMOylation and SENP3 regulate STAT3 activation in head and neck cancer.
Leukemia
SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress.
Liver Diseases
SUMO-specific protease 3 is a key regulator for hepatic lipid metabolism in non-alcoholic fatty liver disease.
Lymphatic Metastasis
Upregulation of SENP3/SMT3IP1 promotes epithelial ovarian cancer progression and forecasts poor prognosis.
Myocardial Ischemia
The desumoylating enzyme sentrin-specific protease 3 contributes to myocardial ischemia reperfusion injury.
Neoplasm Metastasis
De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells.
Neoplasm Metastasis
Upregulation of SENP3/SMT3IP1 promotes epithelial ovarian cancer progression and forecasts poor prognosis.
Neoplasms
An upregulation of SENP3 after spinal cord injury: implications for neuronal apoptosis.
Neoplasms
Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3.
Neoplasms
Assessment of SENP3-interacting proteins in hepatocytes treated with diethylnitrosamine by BioID assay.
Neoplasms
De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells.
Neoplasms
E2F1 sumoylation as a protective cellular mechanism in oxidative stress response.
Neoplasms
High SENP3 Expression Promotes Cell Migration, Invasion, and Proliferation by Modulating DNA Methylation of E-Cadherin in Osteosarcoma.
Neoplasms
Nuclear Nrf2 Activity in Laryngeal Carcinoma is Regulated by SENP3 After Cisplatin-Induced Reactive Oxygen Species Stress.
Neoplasms
Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation.
Neoplasms
Redox-sensitive enzyme SENP3 mediates vascular remodeling via de-SUMOylation of ?-catenin and regulation of its stability.
Neoplasms
SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation.
Neoplasms
SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation.
Neoplasms
SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function.
Neoplasms
SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress.
Neoplasms
SUMO Losing Balance: SUMO Proteases Disrupt SUMO Homeostasis to Facilitate Cancer Development and Progression.
Neoplasms
The Critical Roles of the SUMO-Specific Protease SENP3 in Human Diseases and Clinical Implications.
Neoplasms
Upregulation of SENP3/SMT3IP1 promotes epithelial ovarian cancer progression and forecasts poor prognosis.
Non-alcoholic Fatty Liver Disease
SUMO-specific protease 3 is a key regulator for hepatic lipid metabolism in non-alcoholic fatty liver disease.
Osteosarcoma
High SENP3 Expression Promotes Cell Migration, Invasion, and Proliferation by Modulating DNA Methylation of E-Cadherin in Osteosarcoma.
Ovarian Neoplasms
Upregulation of SENP3/SMT3IP1 promotes epithelial ovarian cancer progression and forecasts poor prognosis.
Prostatic Neoplasms
SUMO Losing Balance: SUMO Proteases Disrupt SUMO Homeostasis to Facilitate Cancer Development and Progression.
Reperfusion Injury
Protective role of the deSUMOylating enzyme SENP3 in myocardial ischemia-reperfusion injury.
Reperfusion Injury
The desumoylating enzyme sentrin-specific protease 3 contributes to myocardial ischemia reperfusion injury.
Sarcoma
High SENP3 Expression Promotes Cell Migration, Invasion, and Proliferation by Modulating DNA Methylation of E-Cadherin in Osteosarcoma.
senp3 peptidase deficiency
DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages.
senp3 peptidase deficiency
SENP3 loss promotes M2 macrophage polarization and breast cancer progression.
senp3 peptidase deficiency
SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes.
Sepsis
SENP3 in monocytes/macrophages up-regulates tissue factor and mediates lipopolysaccharide-induced acute lung injury by enhancing JNK phosphorylation.
Shock, Septic
DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages.
Spinal Cord Injuries
An upregulation of SENP3 after spinal cord injury: implications for neuronal apoptosis.
Squamous Cell Carcinoma of Head and Neck
Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation.
Starvation
A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3.
Stomach Neoplasms
De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells.
Stomach Neoplasms
SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation.
Subarachnoid Hemorrhage
Expression and Cell Distribution of SENP3 in the Cerebral Cortex After Experimental Subarachnoid Hemorrhage in Rats: A Pilot Study.
Subarachnoid Hemorrhage
Inhibition of SENP3 by lentivirus induces suppression of apoptosis in experimental subarachnoid hemorrhage in rats.
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