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Disease on EC 3.4.22.B72 - SENP3 peptidase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acute Lung Injury
SENP3 in monocytes/macrophages up-regulates tissue factor and mediates lipopolysaccharide-induced acute lung injury by enhancing JNK phosphorylation.
Brain Injuries
Expression and Cell Distribution of SENP3 in the Cerebral Cortex After Experimental Subarachnoid Hemorrhage in Rats: A Pilot Study.
Brain Injuries, Traumatic
Expression and Cell Distribution of SENP3 in Brain Tissue After Traumatic Brain Injury in Mice: A Pilot Study.
Breast Neoplasms
E2F1 sumoylation as a protective cellular mechanism in oxidative stress response.
SENP3 loss promotes M2 macrophage polarization and breast cancer progression.
Carcinogenesis
High SENP3 Expression Promotes Cell Migration, Invasion, and Proliferation by Modulating DNA Methylation of E-Cadherin in Osteosarcoma.
Mitotic Phosphorylation of SENP3 Regulates De-SUMOylation of Chromosome-Associated Proteins and Chromosome Stability.
Upregulation of SENP3/SMT3IP1 promotes epithelial ovarian cancer progression and forecasts poor prognosis.
Carcinoma
Nuclear Nrf2 Activity in Laryngeal Carcinoma is Regulated by SENP3 After Cisplatin-Induced Reactive Oxygen Species Stress.
Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation.
SUMOylation and SENP3 regulate STAT3 activation in head and neck cancer.
Carcinoma, Hepatocellular
Combined identification of ARID1A, CSMD1, and SENP3 as effective prognostic biomarkers for hepatocellular carcinoma.
Carcinoma, Ovarian Epithelial
Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC).
Upregulation of SENP3/SMT3IP1 promotes epithelial ovarian cancer progression and forecasts poor prognosis.
Cardiovascular Diseases
The Critical Roles of the SUMO-Specific Protease SENP3 in Human Diseases and Clinical Implications.
Colonic Neoplasms
SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress.
Colorectal Neoplasms
SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function.
Epilepsy
SUMO proteases SENP3 and SENP5 spatiotemporally regulate the kinase activity of Aurora A.
Fatty Liver
SUMO-specific protease 3 is a key regulator for hepatic lipid metabolism in non-alcoholic fatty liver disease.
Head and Neck Neoplasms
SUMOylation and SENP3 regulate STAT3 activation in head and neck cancer.
Leukemia
SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress.
Liver Diseases
SUMO-specific protease 3 is a key regulator for hepatic lipid metabolism in non-alcoholic fatty liver disease.
Lymphatic Metastasis
Upregulation of SENP3/SMT3IP1 promotes epithelial ovarian cancer progression and forecasts poor prognosis.
Myocardial Ischemia
The desumoylating enzyme sentrin-specific protease 3 contributes to myocardial ischemia reperfusion injury.
Neoplasm Metastasis
De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells.
Upregulation of SENP3/SMT3IP1 promotes epithelial ovarian cancer progression and forecasts poor prognosis.
Neoplasms
An upregulation of SENP3 after spinal cord injury: implications for neuronal apoptosis.
Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3.
Assessment of SENP3-interacting proteins in hepatocytes treated with diethylnitrosamine by BioID assay.
De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells.
E2F1 sumoylation as a protective cellular mechanism in oxidative stress response.
High SENP3 Expression Promotes Cell Migration, Invasion, and Proliferation by Modulating DNA Methylation of E-Cadherin in Osteosarcoma.
Nuclear Nrf2 Activity in Laryngeal Carcinoma is Regulated by SENP3 After Cisplatin-Induced Reactive Oxygen Species Stress.
Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation.
Redox-sensitive enzyme SENP3 mediates vascular remodeling via de-SUMOylation of ?-catenin and regulation of its stability.
SENP3 loss promotes M2 macrophage polarization and breast cancer progression.
SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation.
SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation.
SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function.
SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress.
SUMO Losing Balance: SUMO Proteases Disrupt SUMO Homeostasis to Facilitate Cancer Development and Progression.
The Critical Roles of the SUMO-Specific Protease SENP3 in Human Diseases and Clinical Implications.
Upregulation of SENP3/SMT3IP1 promotes epithelial ovarian cancer progression and forecasts poor prognosis.
Non-alcoholic Fatty Liver Disease
SUMO-specific protease 3 is a key regulator for hepatic lipid metabolism in non-alcoholic fatty liver disease.
Osteosarcoma
High SENP3 Expression Promotes Cell Migration, Invasion, and Proliferation by Modulating DNA Methylation of E-Cadherin in Osteosarcoma.
Ovarian Neoplasms
Upregulation of SENP3/SMT3IP1 promotes epithelial ovarian cancer progression and forecasts poor prognosis.
Prostatic Neoplasms
SUMO Losing Balance: SUMO Proteases Disrupt SUMO Homeostasis to Facilitate Cancer Development and Progression.
Reperfusion Injury
Protective role of the deSUMOylating enzyme SENP3 in myocardial ischemia-reperfusion injury.
The desumoylating enzyme sentrin-specific protease 3 contributes to myocardial ischemia reperfusion injury.
Sarcoma
High SENP3 Expression Promotes Cell Migration, Invasion, and Proliferation by Modulating DNA Methylation of E-Cadherin in Osteosarcoma.
senp3 peptidase deficiency
DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages.
SENP3 loss promotes M2 macrophage polarization and breast cancer progression.
SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes.
Sepsis
SENP3 in monocytes/macrophages up-regulates tissue factor and mediates lipopolysaccharide-induced acute lung injury by enhancing JNK phosphorylation.
Shock, Septic
DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages.
Spinal Cord Injuries
An upregulation of SENP3 after spinal cord injury: implications for neuronal apoptosis.
Squamous Cell Carcinoma of Head and Neck
Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation.
Starvation
A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3.
Stomach Neoplasms
De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells.
SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation.
Subarachnoid Hemorrhage
Expression and Cell Distribution of SENP3 in the Cerebral Cortex After Experimental Subarachnoid Hemorrhage in Rats: A Pilot Study.
Inhibition of SENP3 by lentivirus induces suppression of apoptosis in experimental subarachnoid hemorrhage in rats.