Reference on EC 3.4.21.68 - t-Plasminogen activator and Organism(s) Rattus norvegicus and UniProt Accession P19637
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lijnen, H.R.; Webb, P.D.; van Hoef, B.; De Cock, F.; Stassen, J.M.; Prior, S.D.; Collen, D.
Biochemical and biological properties of a recombinant tissue-type plasminogen activator derived from the rat JMI-229 cell line
Thromb. Haemost.
67
239-247
1992
Rattus norvegicus
Medina, M.G.; Ledesma, M.D.; Dominguez, J.E.; Medina, M.; Zafra, D.; Alameda, F.; Dotti, C.G.; Navarro, P.
Tissue plasminogen activator mediates amyloid-induced neurotoxicity via Erk1/2 activation
EMBO J.
24
1706-1716
2005
Mus musculus (P11214), Rattus norvegicus (P19637)
Hu, K.; Yang, J.; Tanaka, S.; Gonias, S.L.; Mars, W.M.; Liu, Y.
Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression
J. Biol. Chem.
281
2120-2127
2006
Mus musculus (P11214), Mus musculus, Rattus norvegicus (P19637)
Komoriya, K.; Kato, Y.; Hayashi, Y.; Ohsuye, K.; Nishigaki, R.; Sugiyama, Y.
Characterization of the hepatic disposition of lanoteplase, a rationally designed variant of tissue plasminogen activator in rodents
Drug Metab. Dispos.
35
469-475
2007
Rattus norvegicus
Adibhatla, R.M.; Hatcher, J.F.
Tissue plasminogen activator (tPA) and matrix metalloproteinases in the pathogenesis of stroke: therapeutic strategies
CNS Neurol. Disord. Drug Targets
7
243-253
2008
Homo sapiens, Mus musculus, Rattus norvegicus, Desmodus rotundus
Lee, S.Y.; Kim, H.J.; Lee, W.J.; Joo, S.H.; Jeon, S.J.; Kim, J.W.; Kim, H.S.; Han, S.H.; Lee, J.; Park, S.H.; Cheong, J.H.; Kim, W.K.; Ko, K.H.; Shin, C.Y.
Differential regulation of matrix metalloproteinase-9 and tissue plasminogen activator activity by the cyclic-AMP system in lipopolysaccharide-stimulated rat primary astrocytes
Neurochem. Res.
33
2324-2334
2008
Rattus norvegicus
David, H.N.; Haelewyn, B.; Risso, J.J.; Colloch, N.; Abraini, J.H.
Xenon is an inhibitor of tissue-plasminogen activator: adverse and beneficial effects in a rat model of thromboembolic stroke
J. Cereb. Blood Flow Metab.
30
718-728
2010
Rattus norvegicus, Homo sapiens (P00750), Homo sapiens
Hultman, K.; Bjoerklund, U.; Hansson, E.; Jern, C.
Potentiating effect of endothelial cells on astrocytic plasminogen activator inhibitor type-1 gene expression in an in vitro model of the blood-brain barrier
Neuroscience
166
408-415
2010
Rattus norvegicus
Zhang, H.; Bi, F.; Xiao, C.; Liu, J.; Wang, Z.; Liu, J.N.; Zhang, J.
The Kringle-2 domain of tissue plasminogen activator significantly reduces mortality and brain infarction in middle cerebral artery occlusion rats
Int. J. Mol. Med.
26
225-230
2010
Rattus norvegicus, Rattus norvegicus Sprague-Dawley
Kim, J.W.; Lee, S.H.; Ko, H.M.; Kwon, K.J.; Cho, K.S.; Choi, C.S.; Park, J.H.; Kim, H.Y.; Lee, J.; Han, S.H.; Ignarro, L.J.; Cheong, J.H.; Kim, W.K.; Shin, C.Y.
Biphasic regulation of tissue plasminogen activator activity in ischemic rat brain and in cultured neural cells: Essential role of astrocyte-derived plasminogen activator inhibitor-1
Neurochem. Int.
58
423-433
2011
Rattus norvegicus, Rattus norvegicus Sprague-Dawley
