Reference on EC 3.1.4.12 - sphingomyelin phosphodiesterase and Organism(s) Mus musculus and UniProt Accession Q9JJY3
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Weitz, G.; Lindl, T.; Hinrichs, U.; Sandhoff, K.
Release of sphingomyelin phosphodiesterase (acid sphingomyelinase) by ammonium chloride from CL 1D mouse L-cells and human fibroblasts. Partial purification and characterization of the exported enzymes
Hoppe-Seyler's Z. Physiol. Chem.
364
863-871
1983
Homo sapiens, Mus musculus
Pentchev, P.G.; Gal, A.E.; Booth, A.D.; Omodeo-Sale, F.; Fouks, J.; Neumeyer, B.A.; Quirk, J.M.; Dawson, G.; Brady, R.O.
A lysosomal storage disorder in mice characterized by a dual deficiency of sphingomyelinase and glucocerebrosidase
Biochim. Biophys. Acta
619
669-679
1980
Mus musculus
Fensome, A.C.; Rodrigues-Lima, F.; Josephs, M.; Paterson, H.F.; Katan, M.
A neutral magnesium-dependent sphingomyelinase isoform associated with intracellular membranes and reversibly inhibited by reactive oxygen species
J. Biol. Chem.
275
1128-1136
2000
Mus musculus
Tomiuk, S.; Zumbansen, M.; Stoffel, W.
Characterization and subcellular localization of murine and human magnesium-dependent neutral sphingomyelinase
J. Biol. Chem.
275
5710-5717
2000
Homo sapiens, Mus musculus
Marchesini, N.; Luberto, C.; Hannun, Y.A.
Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism
J. Biol. Chem.
278
13775-13783
2003
Mus musculus (Q9JJY3), Mus musculus
Jensen, J.M.; Forl, M.; Winoto-Morbach, S.; Seite, S.; Schunck, M.; Proksch, E.; Schutze, S.
Acid and neutral sphingomyelinase, ceramide synthase, and acid ceramidase activities in cutaneous aging
Exp. Dermatol.
14
609-618
2005
Mus musculus
Albi, E.; Cataldi, S.; Bartoccini, E.; Magni, M.V.; Marini, F.; Mazzoni, F.; Rainaldi, G.; Evangelista, M.; Garcia-Gil, M.
Nuclear sphingomyelin pathway in serum deprivation-induced apoptosis of embryonic hippocampal cells
J. Cell. Physiol.
206
189-195
2006
Mus musculus
Soloviev, A.; Schwarz, E.M.; Darowish, M.; O'Keefe, R.J.
Sphingomyelinase mediates macrophage activation by titanium particles independent of phagocytosis: a role for free radicals, NFkappaB, and TNFalpha
J. Orthop. Res.
23
1258-1265
2005
Mus musculus
AAubin, I.; Adams, C.P.; Opsahl, S.; Septier, D.; Bishop, C.E.; Auge, N.; Salvayre, R.; Negre-Salvayre, A.; Goldberg, M.; Guenet, J.L.; Poirier, C.
A deletion in the gene encoding sphingomyelin phosphodiesterase 3 (Smpd3) results in osteogenesis and dentinogenesis imperfecta in the mouse
Nat. Genet.
37
803-805
2005
Mus musculus (Q9JJY3), Mus musculus
Stoffel, W.; Jenke, B.; Block, B.; Zumbansen, M.; Koebke, J.
Neutral sphingomyelinase 2 (smpd3) in the control of postnatal growth and development
Proc. Natl. Acad. Sci. USA
102
4554-4559
2005
Mus musculus (Q9JJY3), Mus musculus
Clarke, C.J.; Hannun, Y.A.
Neutral sphingomyelinases and nSMase2: bridging the gaps
Biochim. Biophys. Acta
1758
1893-1901
2006
Bos taurus, Homo sapiens, Mus musculus, Rattus norvegicus
Duan, R.
Sphingomyelinase and ceramidase in the intestinal tract
Eur. J. Lipid Sci. Technol.
109
987-993
2007
Homo sapiens, Mus musculus, Rattus norvegicus
-
Llacuna, L.; Mari, M.; Garcia-Ruiz, C.; Fernandez-Checa, J.C.; Morales, A.
Critical role of acidic sphingomyelinase in murine hepatic ischemia-reperfusion injury
Hepatology
44
561-572
2006
Mus musculus
McCollister, B.D.; Myers, J.T.; Jones-Carson, J.; Voelker, D.R.; Vazquez-Torres, A.
Constitutive acid sphingomyelinase enhances early and late macrophage killing of Salmonella enterica serovar Typhimurium
Infect. Immun.
75
5346-5352
2007
Mus musculus
Zhang, P.; Li, B.; Gao, S.; Duan, R.D.
Dietary sphingomyelin inhibits colonic tumorigenesis with an up-regulation of alkaline sphingomyelinase expression in ICR mice
Anticancer Res.
28
3631-3635
2009
Mus musculus
Schramm, M.; Herz, J.; Haas, A.; Kroenke, M.; Utermoehlen, O.
Acid sphingomyelinase is required for efficient phago-lysosomal fusion
Cell. Microbiol.
10
1839-1853
2008
Mus musculus
Bianco, F.; Perrotta, C.; Novellino, L.; Francolini, M.; Riganti, L.; Menna, E.; Saglietti, L.; Schuchman, E.H.; Furlan, R.; Clementi, E.; Matteoli, M.; Verderio, C.
Acid sphingomyelinase activity triggers microparticle release from glial cells
EMBO J.
28
1043-1054
2009
Mus musculus
Zhang, Y.; Li, X.; Carpinteiro, A.; Gulbins, E.
Acid sphingomyelinase amplifies redox signaling in Pseudomonas aeruginosa-induced macrophage apoptosis
J. Immunol.
181
4247-4254
2008
Mus musculus
Ohlsson, L.; Hjelte, L.; Huehn, M.; Scholte, B.J.; Wilke, M.; Flodstroem-Tullberg, M.; Nilsson, A.
Expression of intestinal and lung alkaline sphingomyelinase and neutral ceramidase in cystic fibrosis f508del transgenic mice
J. Pediatr. Gastroenterol. Nutr.
47
547-554
2008
Mus musculus
Henkes, L.E.; Sullivan, B.T.; Lynch, M.P.; Kolesnick, R.; Arsenault, D.; Puder, M.; Davis, J.S.; Rueda, B.R.
Acid sphingomyelinase involvement in tumor necrosis factor alpha-regulated vascular and steroid disruption during luteolysis in vivo
Proc. Natl. Acad. Sci. USA
105
7670-7675
2008
Mus musculus
von Bismarck, P.; Wistaedt, C.F.; Klemm, K.; Winoto-Morbach, S.; Uhlig, U.; Schuetze, S.; Adam, D.; Lachmann, B.; Uhlig, S.; Krause, M.F.
Improved pulmonary function by acid sphingomyelinase inhibition in a newborn piglet lavage model
Am. J. Respir. Crit. Care Med.
177
1233-1241
2008
Mus musculus, Sus scrofa
Wu, B.X.; Rajagopalan, V.; Roddy, P.L.; Clarke, C.J.; Hannun, Y.A.
Identification and characterization of murine mitochondrial-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5
J. Biol. Chem.
285
17993-18002
2010
Mus musculus (D6MZJ6), Mus musculus
Bao, X.; Ogawa, T.; Se, S.; Akiyama, M.; Bahtiar, A.; Takeya, T.; Ishida-Kitagawa, N.
Acid sphingomyelinase regulates osteoclastogenesis by modulating sphingosine kinases downstream of RANKL signaling
Biochem. Biophys. Res. Commun.
405
533-537
2011
Mus musculus
Osawa, Y.; Seki, E.; Kodama, Y.; Suetsugu, A.; Miura, K.; Adachi, M.; Ito, H.; Shiratori, Y.; Banno, Y.; Olefsky, J.M.; Nagaki, M.; Moriwaki, H.; Brenner, D.A.; Seishima, M.
Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression
FASEB J.
25
1133-1144
2011
Mus musculus, Mus musculus C57/BL6J, Rattus norvegicus, Rattus norvegicus Sprague-Dawley
Wu, B.X.; Clarke, C.J.; Matmati, N.; Montefusco, D.; Bartke, N.; Hannun, Y.A.
Identification of novel anionic phospholipid binding domains in neutral sphingomyelinase 2 with selective binding preference
J. Biol. Chem.
286
22362-22371
2011
Mus musculus
Dotson Ii, P.P.; Karakashian, A.A.; Nikolova-Karakashian, M.N.
Neutral sphingomyelinase-2 is a redox sensitive enzyme: role of catalytic cysteine residues in regulation of enzymatic activity through changes in oligomeric state
Biochem. J.
465
371-382
2015
Mus musculus (Q9JJY3), Mus musculus
Yang, W.; Schmid, E.; Nurbaeva, M.K.; Szteyn, K.; Leibrock, C.; Yan, J.; Schaller, M.; Gulbins, E.; Shumilina, E.; Lang, F.
Role of acid sphingomyelinase in the regulation of mast cell function
Clin. Exp. Allergy
44
79-90
2014
Mus musculus
Muehle, C.; Huttner, H.B.; Walter, S.; Reichel, M.; Canneva, F.; Lewczuk, P.; Gulbins, E.; Kornhuber, J.
Characterization of acid sphingomyelinase activity in human cerebrospinal fluid
PLoS ONE
8
e62912
2013
Homo sapiens, Mus musculus
Supinski, G.S.; Alimov, A.P.; Wang, L.; Song, X.H.; Callahan, L.A.
Neutral sphingomyelinase 2 is required for cytokine-induced skeletal muscle calpain activation
Am. J. Physiol. Lung Cell Mol. Physiol.
309
L614-L624
2015
Mus musculus
Gorelik, A.; Heinz, L.X.; Illes, K.; Superti-Furga, G.; Nagar, B.
Crystal structure of the acid sphingomyelinase-like phosphodiesterase SMPDL3B provides insights into determinants of substrate specificity
J. Biol. Chem.
291
24054-24064
2016
Mus musculus (P58242), Mus musculus
