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ATP + D-fructose
ADP + D-fructose 6-phosphate
ATP + D-glucose
ADP + D-glucose 6-phosphate
ATP + D-mannose
ADP + D-mannose 6-phosphate
CTP + D-fructose
CDP + D-fructose 6-phosphate
D-fructose + ATP
D-fructose 6-phosphate + ADP
dATP + D-fructose
dADP + D-fructose 6-phosphate
GTP + D-fructose
GDP + D-fructose 6-phosphate
ITP + D-fructose
IDP + D-fructose 6-phosphate
TTP + D-fructose
TDP + D-fructose 6-phosphate
UTP + D-fructose
UDP + D-fructose 6-phosphate
additional information
?
-
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
to enter metabolism, fructose is phosphorylated by a fructokinase
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
no activity with ribose, xylose, fucose, glucose, tagatose or arabinose
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
highly specific for D-fructose
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
specific for fructose
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
specific for fructose
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
high specificity for fructose but no affinity for glucose
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
the first step in fructose metabolism is mediated by fructokinase
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
specific for fructose
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
highly specific for D-fructose, both isoforms
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
sucrose to starch synthetic pathway
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
higher affinity for ATP than for other NTPs
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
best phosphate donor for isozymes FK-II and FK-III
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
sucrose to starch synthetic pathway
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
specific for fructose
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
inducible enzyme
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
highly specific for D-fructose, minor products are D-fructose 2-phosphate and D-fructose-3 phosphate
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
specific for fructose
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
specific for fructose and ATP
-
?
ATP + D-glucose
ADP + D-glucose 6-phosphate
-
-
-
?
ATP + D-glucose
ADP + D-glucose 6-phosphate
-
-
-
-
?
ATP + D-glucose
ADP + D-glucose 6-phosphate
-
low activity
-
-
?
ATP + D-glucose
ADP + D-glucose 6-phosphate
-
isoform FRK1, 1.6% of activity with D-fructose, isoform FRK2, 7.8% of activity with D-fructose
-
-
?
ATP + D-glucose
ADP + D-glucose 6-phosphate
-
isoenzyme FK-I and FK-II less than 5% of the activity with fructose
-
-
?
ATP + D-glucose
ADP + D-glucose 6-phosphate
-
FK-III no activity
-
-
?
ATP + D-mannose
ADP + D-mannose 6-phosphate
-
-
-
?
ATP + D-mannose
ADP + D-mannose 6-phosphate
-
-
-
?
ATP + D-mannose
ADP + D-mannose 6-phosphate
-
D-fructose and D-mannose phosphorylated at equivalent rates
-
?
ATP + D-mannose
ADP + D-mannose 6-phosphate
-
low activity
-
-
?
ATP + D-mannose
ADP + D-mannose 6-phosphate
-
isoform FRK1, 2.2% of activity with D-fructose, isoform FRK2, 2.4% of activity with D-fructose
-
-
?
ATP + D-mannose
ADP + D-mannose 6-phosphate
-
isoenzyme FK-I and FK-II low activity, less than 5% of D-fructose, FK-III no activity
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
-
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
6% of activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
higher activity than with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
40% of the activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
isoform FRK1, 35% of activity with ATP, isoform FRK2, 83% of activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
-
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
30% of the activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
16% of activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
18% of the activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
7.4times higher activity than with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
no activity
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
very low activity
-
-
?
D-fructose + ATP
D-fructose 6-phosphate + ADP
-
-
-
-
?
D-fructose + ATP
D-fructose 6-phosphate + ADP
-
-
-
-
?
D-fructose + ATP
D-fructose 6-phosphate + ADP
-
-
-
-
?
dATP + D-fructose
dADP + D-fructose 6-phosphate
-
-
-
-
?
dATP + D-fructose
dADP + D-fructose 6-phosphate
-
90% of the activity with ATP
-
-
?
dATP + D-fructose
dADP + D-fructose 6-phosphate
-
90% of the activity with ATP
-
-
?
dATP + D-fructose
dADP + D-fructose 6-phosphate
-
80% of the activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
-
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
23% of activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
-
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
30% of the activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
30% of the activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
isoform FRK1, 23% of activity with ATP, isoform FRK2, 135% of activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
-
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
-
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
-
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
best phosphate donor for isozyme FK-I
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
50% of the activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
62% of activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
-
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
3fold higher activity than with ATP
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
-
78% of activity with ATP
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
-
-
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
-
25% of the activity with ATP
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
-
25% of the activity with ATP
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
-
60% of the activity with ATP
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
-
73% of activity with ATP
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
-
-
-
-
?
TTP + D-fructose
TDP + D-fructose 6-phosphate
-
-
-
-
?
TTP + D-fructose
TDP + D-fructose 6-phosphate
-
0.18% of activity with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
-
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
higher activity than with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
-
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
-
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
80% of the activity with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
80% of the activity with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
isoform FRK1, 39% of activity with ATP, isoform FRK2, 84% of activity with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
-
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
-
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
20% of the activity with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
16% of activity with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
14% of the activity with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
-
-
-
?
additional information
?
-
-
no substrate: D-glucose
-
-
?
additional information
?
-
no substrates: glucose, galactose
-
-
?
additional information
?
-
-
no substrates: glucose, galactose
-
-
?
additional information
?
-
-
very low activity as phosphate donors: dGTP, TTP, XTP
-
-
?
additional information
?
-
-
-
-
-
?
additional information
?
-
-
no substrate: L-sorbose
-
-
?
additional information
?
-
-
discussion of possible significance of the enzyme in plant carbohydrate metabolism
-
-
?
additional information
?
-
-
no substrate: L-sorbose
-
-
?
additional information
?
-
-
no substrate: D-mannose
-
-
?
additional information
?
-
-
no substrate: D-glucose
-
-
?
additional information
?
-
no substrate: glucose
-
-
?
additional information
?
-
-
no substrate: D-mannose
-
-
?
additional information
?
-
-
no substrate: D-glucose
-
-
?
additional information
?
-
-
no substrate: D-mannose
-
-
?
additional information
?
-
-
no substrate: D-glucose
-
-
?
additional information
?
-
-
no substrate: D-glucose
-
-
?
additional information
?
-
-
no substrate: D-glucose
-
-
?
additional information
?
-
-
no substrate: ADP, GDP, phosphoenolpyruvate, diphosphate
-
-
?
additional information
?
-
no substrate: glucose
-
-
?
additional information
?
-
no substrate: glucose
-
-
?
additional information
?
-
-
no activity with GTP
-
-
?
additional information
?
-
-
no substrate: D-mannose
-
-
?
additional information
?
-
-
no substrate: D-glucose
-
-
?
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Yamashita, Y.; Ashihara, H.
Characterization of hexokinase and fructokinase from suspension-cultured Catharanthus roseus cells
Z. Naturforsch. C
43
827-834
1988
Catharanthus roseus
-
brenda
Renz, A.; Merlo, L.; Stitt, M.
Partial purification from potato tubers of three fructokinases and three hexokinases which show differing organ and developmental specificity
Planta
190
156-165
1993
Solanum tuberosum
-
brenda
Renz, A.; Stitt, M.
Substrate specificity and product inhibition of different forms of fructokinases and hexokinases in developing potato tubers
Planta
190
166-175
1993
Solanum tuberosum
-
brenda
Doelle, H.W.
Kinetic characteristics and regulatory mechanisms of glucokinase and fructokinase from Zymomonas mobilis
Eur. J. Appl. Microbiol. Biotechnol.
14
241-246
1982
Zymomonas mobilis
-
brenda
Medina, A.; Sols, A.
A specific fructokinase in pea
Biochim. Biophys. Acta
19
378-379
1956
Pisum sativum
brenda
Pastuszak, I.; Szymona, M.
Isolation of a specific ATP:D-fructose 6-phosphotransferase from Mycobacterium phlei
Ann. Univ. Mariae Curie Sklodowska Med.
36
1-11
1981
Mycolicibacterium phlei
brenda
Turner, J.F.; Harrison, D.D.; Copeland, L.
Fructokinase (fraction IV) of pea seeds
Plant Physiol.
60
666-669
1977
Pisum sativum
brenda
Bueding, E.; MacKinnon, J.A.
Hexokinases of Schistosoma mansonii
J. Biol. Chem.
215
495-506
1955
Schistosoma mansoni
brenda
Anderson, R.L.; Sapico, V.L.
D-fructose (D-mannose) kinase
Methods Enzymol.
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