Reference on EC 1.14.19.6 - acyl-CoA (9+3)-desaturase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Wilson, R.A.; Calvo, A.M.; Chang, P.K.; Keller, N.P.
Characterization of the Aspergillus parasiticus DELTA12-desaturase gene: A role for lipid metabolism in the Aspergillus-seed interaction
Microbiology
150
2881-2888
2004
Aspergillus parasiticus
Peyou-Ndi, M.M.; Watts, J.L.; Browse, J.
Identification and characterization of an animal DELTA12 fatty acid desaturase gene by heterologous expression in Saccharomyces cerevisiae
Arch. Biochem. Biophys.
376
399-408
2000
Caenorhabditis elegans
Borgeson, C.E.; De Renobales, M.; Blomquist, G.J.
Characterization of the DELTA12 desaturase in the American cockroach, Periplaneta americana: the nature of the substrate
Biochim. Biophys. Acta
1047
135-140
1990
Periplaneta americana
Jurenka, R.A.
Biosynthetic pathway for producing the sex pheromone component (Z,E)-9,12-tetradecadienyl acetate in moths involves a DELTA12 desaturase
Cell. Mol. Life Sci.
53
501-505
1997
Cadra cautella
Sakuradani, E.; Kobayashi, M.; Ashikari, T.; Shimizu, S.
Identification of DELTA12-fatty acid desaturase from arachidonic acid-producing Mortierella fungus by heterologous expression in the yeast Saccharomyces cerevisiae and the fungus Aspergillus oryzae
Eur. J. Biochem.
261
812-820
1999
Mortierella alpina (Q9Y8H5), Mortierella alpina 1S-4 (Q9Y8H5)
Borgeson, C.E.; Blomquist, G.J.
Subcellular location of the DELTA12-desaturase rules out bacteriocyte contribution to linoleate biosynthesis in the house cricket and the American cockroach
Insect Biochem. Mol. Biol.
23
297-302
1993
Periplaneta americana, Acheta domesticus
-
Avery, S.V.; Lloyd, D.; Harwood, J.L.
Changes in membrane fatty acid composition and DELTA12-desaturase activity during growth of Acanthamoeba castellanii in batch culture
J. Eukaryot. Microbiol.
41
396-401
1994
Acanthamoeba castellanii
-
Nugier-Chauvin, C.; Fauconnot, L.; Daligault, F.; Patin, H.
Enantioselective oxidation of thiafatty acids by an algal DELTA12-desaturase
J. Mol. Catal. B
11
1007-1012
2001
Chlorella vulgaris
-
Lomascolo, A.; Dubreucq, E.; Galzy, P.
Study of the DELTA12-desaturase system of Lipomyces starkeyi
Lipids
31
253-259
1996
Lipomyces starkeyi, Lipomyces starkeyi CBS 1807
Avery, S.V.; Rutter, A.J.; Harwood, J.L.; Lloyd, D.
Oxygen-dependent low-temperature DELTA12 (n6)-desaturase induction and alteration of fatty acid composition in Acanthamoeba castellanii
Microbiology
142
2213-2221
1996
Acanthamoeba castellanii
-
Sakamoto, T.; Bryant, D.A.
Synergistic effect of high-light and low temperature on cell growth of the DELTA12 fatty acid desaturase mutant in Synechococcus sp. PCC 7002
Photosynth. Res.
72
231-242
2002
Synechococcus sp. PCC 7002
Galle, A.M.; Oursel, A.; Joseph, M.; Kader, J.C.
Solubilization of membrane bound DELTA12- and DELTA6-fatty acid desaturases from borage seeds
Phytochemistry
45
1587-1590
1997
Borago officinalis
-
Domergue, F.; Spiekermann, P.; Lerchl, J.; Beckmann, C.; Kilian, O.; Kroth, P.G.; Boland, W.; Zahringer, U.; Heinz, E.
New insight into Phaeodactylum tricornutum fatty acid metabolism. Cloning and functional characterization of plastidial and microsomal DELTA12-fatty acid desaturases
Plant Physiol.
131
1648-1660
2003
Phaeodactylum tricornutum
Saeki, K.; Matsumoto, K.; Kinoshita, M.; Suzuki, I.; Tasaka, Y.; Kano, K.; Taguchi, Y.; Mikami, K.; Hirabayashi, M.; Kashiwazaki, N.; Hosoi, Y.; Murata, N.; Iritani, A.
Functional expression of a DELTA12 fatty acid desaturase gene from spinach in transgenic pigs
Proc. Natl. Acad. Sci. USA
101
6361-6366
2004
Spinacia oleracea (Q8H943)
Fofana, B.; Cloutier, S.; Duguid, S.; Ching, J.; Rampitsch, C.
Gene expression of stearoyl-ACP desaturase and delta12 fatty acid desaturase 2 is modulated during seed development of flax (Linum usitatissimum)
Lipids
41
705-712
2006
Linum usitatissimum
Zhang, S.; Sakuradani, E.; Ito, K.; Shimizu, S.
Identification of a novel bifunctional DELTA12/DELTA15 fatty acid desaturase from a basidiomycete, Coprinus cinereus TD#822-2
FEBS Lett.
581
315-319
2007
Coprinopsis cinerea (A2A1C4), Coprinopsis cinerea TD#822-2 (A2A1C4), Coprinopsis cinerea TD822-2 (A2A1C4)
Sakai, H.; Kajiwara, S.
Cloning and functional characterization of a DELTA12 fatty acid desaturase gene from the basidiomycete Lentinula edodes
Mol. Genet. Genomics
273
336-341
2005
Lentinula edodes (Q65YX3), Lentinula edodes
Damude, H.G.; Zhang, H.; Farrall, L.; Ripp, K.G.; Tomb, J.F.; Hollerbach, D.; Yadav, N.S.
Identification of bifunctional delta12/omega3 fatty acid desaturases for improving the ratio of omega3 to omega6 fatty acids in microbes and plants
Proc. Natl. Acad. Sci. USA
103
9446-9451
2006
Fusarium verticillioides (Q27ZJ7)
Li, M.C.; Li, H.; Wei, D.S.; Xing, L.J.
Cloning and molecular characterization of DELTA12-fatty acid desaturase gene from Mortierella isabellina
World J. Gastroenterol.
12
3373-3379
2006
Umbelopsis isabellina (P59668)
Kainou, K.; Kamisaka, Y.; Kimura, K.; Uemura, H.
Isolation of DELTA12 and omega3-fatty acid desaturase genes from the yeast Kluyveromyces lactis and their heterologous expression to produce linoleic and alpha-linolenic acids in Saccharomyces cerevisiae
Yeast
23
605-612
2006
Kluyveromyces lactis, Kluyveromyces lactis NK1
Cipak, A.; Jaganjac, M.; Tehlivets, O.; Kohlwein, S.D.; Zarkovic, N.
Adaptation to oxidative stress induced by polyunsaturated fatty acids in yeast
Biochim. Biophys. Acta
1781
283-287
2008
Hevea brasiliensis
Niu, B.; Ye, H.; Xu, Y.; Wang, S.; Chen, P.; Peng, S.; Ou, Y.; Tang, L.; Chen, F.
Cloning and characterization of a novel DELTA12-fatty acid desaturase gene from the tree Sapium sebiferum
Biotechnol. Lett.
29
959-964
2007
Triadica sebifera (A5J295), Triadica sebifera
Hoffmann, M.; Hornung, E.; Busch, S.; Kassner, N.; Ternes, P.; Braus, G.H.; Feussner, I.
A small membrane-peripheral region close to the active center determines regioselectivity of membrane-bound fatty acid desaturases from Aspergillus nidulans
J. Biol. Chem.
282
26666-26674
2007
Aspergillus nidulans (Q5AWX6), Aspergillus nidulans (Q5BEJ3), Aspergillus nidulans, Aspergillus nidulans FGSC A4 (Q5AWX6), Aspergillus nidulans FGSC A4 (Q5BEJ3)
Kargiotidou, A.; Deli, D.; Galanopoulou, D.; Tsaftaris, A.; Farmaki, T.
Low temperature and light regulate delta 12 fatty acid desaturases (FAD2) at a transcriptional level in cotton (Gossypium hirsutum)
J. Exp. Bot.
59
2043-2056
2008
Gossypium hirsutum (Q8W2B9), Gossypium hirsutum
Yin, D.; Cui, D.; Jia, B.
Construction of a high-efficient expression vector of Delta12 fatty acid desaturase in peanut and its prokaryotical expression
J. Genet. Genomics
34
81-88
2007
Arachis hypogaea
Meesapyodsuk, D.; Qiu, X.
An oleate hydroxylase from the fungus Claviceps purpurea: cloning, functional analysis, and expression in Arabidopsis
Plant Physiol.
147
1325-1333
2008
Claviceps purpurea
Oura, T.; Kajiwara, S.
Substrate specificity and regioselectivity of DELTA12 and omega3 fatty acid desaturases from Saccharomyces kluyveri
Biosci. Biotechnol. Biochem.
72
3174-3179
2008
Lachancea kluyveri
Zhou, X.R.; Horne, I.; Damcevski, K.; Haritos, V.; Green, A.; Singh, S.
Isolation and functional characterization of two independently-evolved fatty acid DELTA12-desaturase genes from insects
Insect Mol. Biol.
17
667-676
2008
Acheta domesticus (B7SB91)
Sakuradani, E.; Abe, T.; Matsumura, K.; Tomi, A.; Shimizu, S.
Identification of mutation sites on DELTA12 desaturase genes from Mortierella alpina 1S-4 mutants
J. Biosci. Bioeng.
107
99-101
2009
Mortierella alpina (Q9Y8H5), Mortierella alpina 1S-4 (Q9Y8H5)
Zhang, D.; Pirtle, I.L.; Park, S.J.; Nampaisansuk, M.; Neogi, P.; Wanjie, S.W.; Pirtle, R.M.; Chapman, K.D.
Identification and expression of a new delta-12 fatty acid desaturase (FAD2-4) gene in upland cotton and its functional expression in yeast and Arabidopsis thaliana plants
Plant Physiol. Biochem.
47
462-471
2009
Gossypium hirsutum (B0FYE4), Gossypium hirsutum
Chen, Q.; Liu, Q.; Wu, Z.; Wang, Z.; Gou, K.
Generation of fad2 transgenic mice that produce omega-6 fatty acids
Sci. China C Life Sci.
52
1048-1054
2009
Gossypium hirsutum
Yazawa, H.; Iwahashi, H.; Kamisaka, Y.; Kimura, K.; Uemura, H.
Production of polyunsaturated fatty acids in yeast Saccharomyces cerevisiae and its relation to alkaline pH tolerance
Yeast
26
167-184
2009
Kluyveromyces lactis
Amiri, R.M.; Yureva, N.O.; Shimshilashvili, K.R.; Goldenkova-Pavlova, I.V.; Pchelkin, V.P.; Kuznitsova, E.I.; Tsydendambaev, V.D.; Trunova, T.I.; Los, D.A.; Jouzani, G.S.; Nosov, A.M.
Expression of acyl-lipid Delta12-desaturase gene in prokaryotic and eukaryotic cells and its effect on cold stress tolerance of potato
J. Integr. Plant Biol.
52
289-297
2010
Synechocystis sp., Synechocystis sp. (P20388)
Ruenwai, R.; Cheevadhanarak, S.; Rachdawong, S.; Tanticharoen, M.; Laoteng, K.
Oxygen-induced expression of DELTA6-, DELTA9- and DELTA12-desaturase genes modulates fatty acid composition in Mucor rouxii
Appl. Microbiol. Biotechnol.
86
327-334
2010
Amylomyces rouxii
Watanabe, T.; Tsuda, S.; Nishimura, H.; Honda, Y.; Watanabe, T.
Characterization of a DELTA12-fatty acid desaturase gene from Ceriporiopsis subvermispora, a selective lignin-degrading fungus
Appl. Microbiol. Biotechnol.
87
215-224
2010
Phanerodontia chrysosporium (D4Q8H2), Gelatoporia subvermispora (D4Q8S6)
Lu, Y.; Chi, X.; Li, Z.; Yang, Q.; Li, F.; Liu, S.; Gan, Q.; Qin, S.
Isolation and characterization of a stress-dependent plastidial DELTA12 fatty acid desaturase from the antarctic microalga Chlorella vulgaris NJ-7
Lipids
45
179-187
2010
Chlorella vulgaris (D3U658), Chlorella vulgaris (E2CT06), Chlorella vulgaris NJ-7 (D3U658), Chlorella vulgaris NJ-7 (E2CT06)
Yan, Z.; Zhuo, L.; Mulan, J.; Xia, W.; Yangmin, G.; Yinbo, Z.; Fenghong, H.
Clone and identification of bifunctional DELTA12/DELTA15 fatty acid desaturase LKFAD15 from Lipomyces kononenkoae
Food Sci. Biotechnol.
22
573-576
2013
Lipomyces kononenkoae, Lipomyces kononenkoae 1714
-
Matsuda, T.; Sakaguchi, K.; Kobayashi, T.; Abe, E.; Kurano, N.; Sato, A.; Okita, Y.; Sugimoto, S.; Hama, Y.; Hayashi, M.; Okino, N.; Ito, M.
Molecular cloning of a Pinguiochrysis pyriformis oleate-specific microsomal DELTA12-fatty acid desaturase and functional analysis in yeasts and thraustochytrids
J. Biochem.
150
375-383
2011
Pinguiochrysis pyriformis, Pinguiochrysis pyriformis MBIC 10872
Zhou, X.; Green, A.; Singh, S.
Caenorhabditis elegans ?12-desaturase FAT-2 is a bifunctional desaturase able to desaturate a diverse range of fatty acid substrates at the DELTA12 and DELTA15 positions
J. Biol. Chem.
286
43644-43650
2011
Caenorhabditis elegans (G5EGA5)
Matsuda, T.; Sakaguchi, K.; Hamaguchi, R.; Kobayashi, T.; Abe, E.; Hama, Y.; Hayashi, M.; Honda, D.; Okita, Y.; Sugimoto, S.; Okino, N.; Ito, M.
Analysis of DELTA12-fatty acid desaturase function revealed that two distinct pathways are active for the synthesis of PUFAs in T. aureum ATCC 34304
J. Lipid Res.
53
1210-1222
2012
Thraustochytrium aureum, Thraustochytrium aureum ATCC 34304
Shi, J.; Cao, Y.; Fan, X.; Li, M.; Wang, Y.; Ming, F.
A rice microsomal delta-12 fatty acid desaturase can enhance resistance to cold stress in yeast and Oryza sativa
Mol. Breed.
29
743-757
2012
Oryza sativa (Q6ZGW6)
-
Demin, I.; Naraikina, N.; Tsydendambaev, V.; Moshkov, I.; Trunova, T.
The effect of potato plant transformation with the gene encoding DELTA12-acyl-lipid desaturase on the CO2 exchange and activities of antioxidant enzymes under hypothermia
Russ. J. Plant Physiol.
60
367-374
2013
Synechocystis sp.
-
Demin I, D.I.; Shimshilashvili C, S.C.; YurEva N, Y.N.; Naraykina N, N.N.; Goldenkova-Pavlova I, G.I.; Los D, L.D.; Nosov A, N.A.; Trunova T, T.T.
Overexpression of the acyl-lipid DELTA12-desaturase gene protects potato plants from low temperature damage
Acta Agron. Hung.
59
87-99
2011
Synechocystis sp. (P20388)
-
Los D.; Horvath I.; Vigh L.; Murata N.
The temperature-dependent expression of the desaturase gene desA in Synechocystis PCC6803
FEBS Lett.
318
57-60
1993
Synechocystis sp. (P20388)
Avelange-Macherel M.-H.; Macherel D.; Wada H.; Murata N.
Site-directed mutagenesis of histidine residues in the DELTA12 acyl-lipid desaturase of Synechocystis
FEBS Lett.
361
111-114
1995
Synechocystis sp. (P20388), Synechocystis sp.
Okada, S.; Zhou, X.R.; Damcevski, K.; Gibb, N.; Wood, C.; Hamberg, M.; Haritos, V.S.
Diversity of DELTA12 fatty acid desaturases in santalaceae and their role in production of seed oil acetylenic fatty acids
J. Biol. Chem.
288
32405-32413
2013
Exocarpos cupressiformis, Santalum acuminatum
Wada, H.; Gombos, Z.; Murata, N.
Enhancement of chilling tolerance of a cyanobacterium by genetic manipulation of fatty acid desaturation
Nature
347
200-203
1990
Synechocystis sp. (P20388)
Bielecka, M.; Kaminski, F.; Adams, I.; Poulson, H.; Sloan, R.; Li, Y.; Larson, T.R.; Winzer, T.; Graham, I.A.
Targeted mutation of DELTA12 and DELTA15 desaturase genes in hemp produce major alterations in seed fatty acid composition including a high oleic hemp oil
Plant Biotechnol. J.
12
613-623
2014
Cannabis sativa (A0A088MFF4)
Sakamoto, T.; Wada, H.; Nishida, I.; Ohmori, M.; Murata, N.
Identification of conserved domains in the DELTA12 desaturases of cyanobacteria
Plant Mol. Biol.
24
643-650
1994
Synechocystis sp. (P20388), Synechococcus sp. (Q55231)
Demin, I.; Deryabin, A.; Sinkevich, M.; Trunova, T.
Insertion of cyanobacterial desA gene coding for DELTA12-acyl-lipid desaturase increases potato plant resistance to oxidative stress induced by hypothermia
Russ. J. Plant Physiol.
55
639-648
2008
Synechocystis sp. (P20388)
-
Astakhova, N.V.; Demin, I.N.; Naraikina, N.V.; Trunova, T.I.
Effect of the desA gene encoding DELTA12 acyl-lipid desaturase on the chloroplast structure and tolerance to hypothermia of potato plants
Russ. J. Plant Physiol.
58
18-23
2011
Synechocystis sp. (P20388)
-
Yureva, N.O.; Kirsanova, S.N.; Kukushkina, L.N.; Pchelkin, V.P.; Sobolkova, G.I.; Nikiforova, K.R.; Goldenkova-Pavlova, I.V.; Nosov, A.M.; Tsydendambaev, V.D.
Expression of the gene encoding DELTA12 acyl-lipid desaturase from Synechocystis sp. PCC 6803 improves potato plant resistance to late blight infection
Russ. J. Plant Physiol.
61
672-678
2014
Synechocystis sp. (P20388)
-
Gerasymenko, I.M.; Sakhno, L.A.; Kyrpa, T.N.; Ostapchuk, A.M.; Hadjiev, T.A.; Goldenkova-Pavlova, I.V.; Sheludko, Y.V.
Characterization of Nicotiana tabacum plants expressing hybrid genes of cyanobacterial DELTA9 or DELTA12 acyl-lipid desaturases and thermostable lichenase
Russ. J. Plant Physiol.
62
283-291
2015
Synechocystis sp. (P20388)
-
Wang, Y.; Zhang, S.; Poetter, M.; Sun, W.; Li, L.; Yang, X.; Jiao, X.; Zhao, Z.K.
Overexpression of DELTA12-fatty acid desaturase in the oleaginous yeast Rhodosporidium toruloides for production of linoleic acid-rich lipids
Appl. Biochem. Biotechnol.
180
1497-1507
2016
Mortierella alpina, Fusarium verticillioides (Q27ZJ7)
Lin, P.; Zhou, C.; Yao, X.; Cao, Y.
Sequence and expression characterization of two genes encoding DELTA-12 fatty acid desaturases from Camellia oleifera
Forest Res.
29
743-751
2016
Camellia oleifera (A0A088NBK4)
-
Sun, R.; Gao, L.; Yu, X.; Zheng, Y.; Li, D.; Wang, X.
Identification of a DELTA12 fatty acid desaturase from oil palm (Elaeis guineensis Jacq.) involved in the biosynthesis of linoleic acid by heterologous expression in Saccharomyces cerevisiae
Gene
591
21-26
2016
Elaeis guineensis (A0A1B0YC62)
Dehghan Nayeri, F.; Yarizade, K.
Bioinformatics study of delta-12 fatty acid desaturase 2 (FAD2) gene in oilseeds
Mol. Biol. Rep.
41
5077-5087
2014
Arachis hypogaea (E6Y9B0), Brassica napus (C3W519), Carthamus tinctorius (E9M2L7), Cucurbita pepo (Q6QUM6), Glycine max (P48631), Olea europaea (Q4QWZ0), Olea europaea subsp. europaea (F2YFG1), Vernicia fordii (Q8GZC3), Vitis labrusca (F8TVX9)
Bielecka, M.; Kaminski, F.; Adams, I.; Poulson, H.; Sloan, R.; Li, Y.; Larson, T.R.; Winzer, T.; Graham, I.A.
Targeted mutation of DELTA12 and DELTA15 desaturase genes in hemp produce major alterations in seed fatty acid composition including a high oleic hemp oil
Plant Biotechnol. J.
12
613-623
2014
Cannabis sativa (A0A088MFF4)
html completed