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Literature summary for 1.14.19.6 extracted from

  • Lomascolo, A.; Dubreucq, E.; Galzy, P.
    Study of the DELTA12-desaturase system of Lipomyces starkeyi (1996), Lipids, 31, 253-259.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
EDTA DELTA12-desaturase system, enzymatic complex Lipomyces starkeyi
Hg2+ DELTA12-desaturase system, enzymatic complex Lipomyces starkeyi
Iodine DELTA12-desaturase system, enzymatic complex Lipomyces starkeyi
iodoacetic acid DELTA12-desaturase system, enzymatic complex Lipomyces starkeyi
N-bromosuccinimide DELTA12-desaturase system, enzymatic complex Lipomyces starkeyi
N-ethyl-5-phenylisoxazolium 3'-sulfonate DELTA12-desaturase system, enzymatic complex Lipomyces starkeyi
NEM DELTA12-desaturase system, enzymatic complex Lipomyces starkeyi
trifluoroacetic acid DELTA12-desaturase system, enzymatic complex Lipomyces starkeyi

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome localization of the DELTA12-desaturase system Lipomyces starkeyi
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ activation, DELTA12-desaturase system, enzymatic complex Lipomyces starkeyi
Mn2+ activation, DELTA12-desaturase system, enzymatic complex Lipomyces starkeyi
Zn2+ activation, DELTA12-desaturase system, enzymatic complex Lipomyces starkeyi

Organism

Organism UniProt Comment Textmining
Lipomyces starkeyi
-
CBS 1807
-
Lipomyces starkeyi CBS 1807
-
CBS 1807
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the DELTA12-desaturase enzymatic complex shows a preference towards oleoyl-CoA versus elaidoyl-CoA. Study of substrate specificity of the DELTA12 desaturase system is difficult due to the involvement of numerous enzymes. At least two activities are involved: in a first step, acyl CoA synthetase catalyzes the formation of oleoyl-CoA from olic acid and CoA, then oleoyl-CoA is desaturated into linoleoyl-CoA. No desaturation occurs when CoA is absent in the reaction medium Lipomyces starkeyi ?
-
?
additional information the DELTA12-desaturase enzymatic complex shows a preference towards oleoyl-CoA versus elaidoyl-CoA. Study of substrate specificity of the DELTA12 desaturase system is difficult due to the involvement of numerous enzymes. At least two activities are involved: in a first step, acyl CoA synthetase catalyzes the formation of oleoyl-CoA from olic acid and CoA, then oleoyl-CoA is desaturated into linoleoyl-CoA. No desaturation occurs when CoA is absent in the reaction medium Lipomyces starkeyi CBS 1807 ?
-
?

Synonyms

Synonyms Comment Organism
DELTA12-desaturase system enzymatic complex Lipomyces starkeyi

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
40
-
DELTA12-desaturase system, enzymatic complex Lipomyces starkeyi

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7 8 DELTA12-desaturase system, enzymatic complex Lipomyces starkeyi