Reference on EC 1.13.11.34 - arachidonate 5-lipoxygenase and Organism(s) Rattus norvegicus and UniProt Accession P12527
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
DeWolf, W.E.
Enzymatic studies on purified 5-lipoxygenase
Lipoxygenases and Their Products (Crooke, S. T. ed. ) Academic Press
105-135
1991
Cavia porcellus, Homo sapiens, Rattus norvegicus, Sus scrofa
-
McMillan, R.M.; Masters, D.J.; Vickers, V.C.; Dicken, M.P.; Jacobs, V.N.
Metabolism of unsaturated fatty acids by RBL-1 5-lipoxygenase: influence of substrate solubility and product inactivation
Biochim. Biophys. Acta
1005
170-176
1989
Rattus norvegicus
Denis, D.; Choo, L.Y.; Riendeau, D.
Activation of 5-lipoxygenase by guanosine 5-O-(3-thiotriphosphate) and other nucleoside phosphorothioates: redox properties of thionucleotide analogs
Arch. Biochem. Biophys.
273
592-596
1989
Rattus norvegicus
Haurand, M.; Flohe, L.
Kinetic studies on arachidonate 5-lipoxygenase from rat basophilic leukemia cells
Biol. Chem. Hoppe-Seyler
369
133-142
1988
Rattus norvegicus
Masters, D.J.; Jacobs, V.N.; Carr, V.J.; McMillan, R.M.
Kinetics of 5-lipoxygenase: influence of substrate solubility and product inactivation
Biochem. Soc. Trans.
16
38-39
1988
Rattus norvegicus
-
Skoog, M.T.; Nichols, J.S.; Wiseman, J.S.
5-Lipoxygenase from rat PMN lysate
Prostaglandins
31
561-576
1986
Rattus norvegicus
Wiseman, J.S.; Skoog, M.T.; Nichols, J.S.; Harrison, B.L.
Kinetics of leukotriene A4 synthesis by 5-lipoxygenase from rat polymorphonuclear leukocytes
Biochemistry
26
5684-5689
1987
Rattus norvegicus
Corey, E.J.; Casman, J.R.; Eckrich, T.M.; Corey, D.R.
A new class of irreversible inhibitors of leukotriene biosynthesis
J. Am. Chem. Soc.
107
713-715
1985
Rattus norvegicus
-
Furukawa, M.; Yoshimoto, T.; Ochi, K.; Yamamoto, S.
Studies on arachidonate 5-lipoxygenase of rat basophilic leukemia cells
Biochim. Biophys. Acta
795
458-465
1984
Rattus norvegicus
Corey, E.J.; Lansbury, P.T.; Cashman, J.R.; Kanter, S.S.
Mechanism of the irreversible deactivation of arachidonate 5-lipoxygenase by 5,6-dehydroarachidonate
J. Am. Chem. Soc.
106
1501-1503
1984
Rattus norvegicus
-
Brock, T.G.; McNish, R.W.; Peters-Golden, M.
Translocation and leukotriene synthetic capacity of nuclear 5-lipoxygenase in rat basophilic leukemia cells and alveolar macrophages
J. Biol. Chem.
270
21652-21658
1995
Homo sapiens, Rattus norvegicus
Brock, T.G.; Paine, R.; Peters-Golden, M.
Localization of 5-lipoxygenase to the nucleus of unstimulated rat basophilic leukemia cells
J. Biol. Chem.
269
22059-22066
1994
Rattus norvegicus
Bell, R.L.; Harris, R.R.
The enzymology and pharmacology of 5-lipoxygenase and 5-lipoxygenase activating protein
Clin. Rev. Allergy Immunol.
17
91-109
1999
Cavia porcellus, Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus, Sus scrofa
Lammers, C.H.; Schweitzer, P.; Facchinetti, P.; Arrang, J.M.; Madamba, S.G.; Siggins, G.R.; Piomelli, D.
Arachidonate 5-lipoxygenase and its activating protein: prominent hippocampal expression and role in somatostatin signaling
J. Neurochem.
66
147-152
1996
Rattus norvegicus
Radmark, O.
Arachidonate 5-lipoxygenase
Prostaglandins
68-69
211-234
2002
Oryctolagus cuniculus, Homo sapiens, Mus musculus, Rattus norvegicus, Solanum tuberosum, Sus scrofa
Brkert, E.; Szellas, D.; Radmark, O.; Steinhilber, D.; Werz, O.
Cell type-dependent activation of 5-lipoxygenase by arachidonic acid
J. Leukocyte Biol.
73
191-200
2003
Homo sapiens, Rattus norvegicus
Schneider, I.; Bucar, F.
Lipoxygenase inhibitors from natural plant sources. Part 1: Medicinal plants with inhibitory activity on arachidonate 5-lipoxygenase and 5-lipoxygenase/cyclooxygenase
Phytother. Res.
19
81-102
2005
Bos taurus, Cavia porcellus, Glycine max, Helianthus tuberosus, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
Hardy, G.; Vergnaud, S.; Lunardi, J.; Peoc'h, M.; Bessard, G.; Stanke-Labesque, F.
5-Lipoxygenase expression and activity in aorta from streptozotocin-induced diabetic rats
Prostaglandins
75
91-103
2005
Rattus norvegicus
Zheng, M.; Zheng, M.; Ye, D.; Deng, Y.; Qiu, S.; Luo, X.; Chen, K.; Liu, H.; Jiang, H.
Indole derivatives as potent inhibitors of 5-lipoxygenase: design, synthesis, biological evaluation, and molecular modeling
Bioorg. Med. Chem. Lett.
17
2414-2420
2007
Rattus norvegicus (P12527)
Radmark, O.; Werz, O.; Steinhilber, D.; Samuelsson, B.
5-Lipoxygenase: regulation of expression and enzyme activity
Trends Biochem. Sci.
32
332-341
2007
Mus musculus, Rattus norvegicus, Homo sapiens (P09917)
Radmark, O.; Samuelsson, B.
5-Lipoxygenase: mechanisms of regulation
J. Lipid Res.
50 Suppl
S40-S45
2009
Homo sapiens, Mus musculus, Rattus norvegicus
Karg, E.M.; Luderer, S.; Pergola, C.; Buehring, U.; Rossi, A.; Northoff, H.; Sautebin, L.; Troschuetz, R.; Werz, O.
Structural optimization and biological evaluation of 2-substituted 5-hydroxyindole-3-carboxylates as potent inhibitors of human 5-lipoxygenase
J. Med. Chem.
52
3474-3483
2009
Homo sapiens, Rattus norvegicus
Cho, Y.S.; Kim, C.H.; Surh, J.H.; Kang, N.S.; Yoo, S.E.; Cheon, H.G.
Identification of 4-[4-(4-fluoro-phenyl)-thiazol-2-ylamino]-2,6-dimethyl-phenol (KR-33749) as an inhibitor of 5-lipoxygenase with potent antiinflammatory activity
Pharmacology
86
65-72
2010
Rattus norvegicus
Khairullina, V.; Taipov, I.; Gerchikov, A.; Zarudii, F.
Structure-activity relationship in a series of natural and synthetic inhibitors of 5-lipoxygenase catalytic activity
Pharm. Chem. J.
46
553-564
2012
Rattus norvegicus
-
