EC Number |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
---|
1.13.11.34 | 764158 |
5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a lipoxin intermediate Reactivity and kinetics with human leukocyte 5-lipoxygenase, platelet 12-lipoxygenase, and reticulocyte 15-lipoxygenase-1 |
Biochemistry |
57 |
6726-6734 |
2018 |
Homo sapiens |
30407793 |
1.13.11.34 | 741898 |
ATP allosterically activates the human 5-lipoxygenase molecular mechanism of arachidonic acid and 5(S)-hydroperoxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid |
Biochemistry |
53 |
4407-4419 |
2014 |
Homo sapiens |
24893149 |
1.13.11.34 | 742001 |
Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LODELTA13, 5-LODELTA4 and 5-LOp12 |
Biochim. Biophys. Acta |
1862 |
561-571 |
2017 |
Homo sapiens |
28257804 |
1.13.11.34 | 741975 |
Characterization of the interaction of human 5-lipoxygenase with its activating protein FLAP |
Biochim. Biophys. Acta |
1851 |
1465-1472 |
2015 |
Homo sapiens |
26327594 |
1.13.11.34 | 741862 |
Characterization of the molecular mechanism of 5-lipoxygenase inhibition by 2-aminothiazoles |
Biochem. Pharmacol. |
123 |
52-62 |
2017 |
Homo sapiens |
27671344 |
1.13.11.34 | 743326 |
Design, synthesis and cellular characterization of a dual inhibitor of 5-lipoxygenase and soluble epoxide hydrolase |
Molecules |
22 |
45 |
2016 |
Homo sapiens |
28036068 |
1.13.11.34 | 765222 |
Design, synthesis, and structure-activity relationship studies of dual inhibitors of soluble epoxide hydrolase and 5-lipoxygenase |
J. Med. Chem. |
63 |
11498-11521 |
2020 |
Homo sapiens |
33044073 |
1.13.11.34 | 765256 |
Different forms of vitamin E and metabolite 13-carboxychromanols inhibit cyclooxygenase-1 and its catalyzed thromboxane in platelets, and tocotrienols and 13-carboxychromanols are competitive inhibitors of 5-lipoxygenase |
J. Nutr. Biochem. |
100 |
108884 |
2022 |
Homo sapiens |
34710615 |
1.13.11.34 | 764622 |
Discovery of a novel 2,5-dihydroxycinnamic acid-based 5-lipoxygenase inhibitor that induces apoptosis and may impair autophagic flux in RCC4 renal cancer cells |
Eur. J. Med. Chem. |
179 |
347-357 |
2019 |
Homo sapiens |
31260889 |
1.13.11.34 | 765477 |
Evaluation of cyrhetrenyl and ferrocenyl precursors as 5-lipoxygenase inhibitors - biological and computational studies |
New J. Chem. |
45 |
13360-13368 |
2021 |
Homo sapiens |
- |