6.3.4.6: urea carboxylase

This is an abbreviated version!
For detailed information about urea carboxylase, go to the full flat file.

Reaction

Synonyms

ATP-urea amidolyase, ATP:urea amidolyase, DUR1,2, EC 3.5.1.45, KLLA0_E08119g, UALase, UCA, Urea amido-lyase, urea amidolyase, urea carboxylase, Urea carboxylase (hydrolysing), Urease (ATP-hydrolysing)

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.4 Other carbon-nitrogen ligases

                6.3.4.6 urea carboxylase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	Activating Compound
1587	AA Sequence
2	Application
1	CAS Registry Number
3	Cloned(Commentary)
13	Cofactor
2	Crystallization (Commentary)
1	Expression
4	General Information
1	General Stability
33	Inhibitors
13	kcat/KM [mM/s]
1	Ki Value [mM]
24	KM Value [mM]
17	Metals/Ions
8	Molecular Weight [Da]
16	Natural Substrates/ Products (Substrates)
65	Organism
6	Pathway
1	PDB ID
5	pH Optimum
3	pH Range
1	pH Stability
17	Protein Variants
6	Purification (Commentary)
2	Reaction
4	Reaction Type
62	Reference
3	Specific Activity [micromol/min/mg]
67	Substrates and Products (Substrate)
11	Subunits
45	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
5	Temperature Stability [°C]
16	Turnover Number [1/s]

Expression

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Expression on EC 6.3.4.6 - urea carboxylase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Expression Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

EXPRESSION

ORGANISM

UNIPROT

LITERATURE

DUR1,2 and urea transporter DUR3 expression is strongly induced by urea, whereas the other putative transporter genes are induced less than twofold. Urea induction of DUR1,2 is reduced in a transcription factor gat1D mutant, strongly reduced in a transcription factor gln3D mutant, and abolished in a gat1D gln3D double mutant. Expression of DUR1,2 and DUR3 is higher in the GP basal media than in YPD medium. Addition of proline or glutamine at 10 mM in the presence of urea significantly repressed expression relative to urea alone. Urea induction of DUR3 is not dependent upon DUR1,2 expression

Candida albicans

-

716145