6.3.2.B2: murein peptide ligase

This is an abbreviated version!
For detailed information about murein peptide ligase, go to the full flat file.

Reaction

Synonyms

Mpl

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.2 Acid—amino-acid ligases (peptide synthases)

                6.3.2.B2 murein peptide ligase

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Results	in table
1	AA Sequence
1	Cloned(Commentary)
1	Cofactor
1	Crystallization (Commentary)
6	General Information
2	Localization
1	Metals/Ions
2	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
2	Organism
1	pH Optimum
1	Purification (Commentary)
1	Reaction
2	Reference
13	Substrates and Products (Substrate)
4	Subunits
2	Synonyms
1	Systematic Name
7	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 6.3.2.B2 - murein peptide ligase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

ATP + L-alanine + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine

2 entries

ATP + L-alanyl-gamma-D-glutamate + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamate

2 entries

ATP + L-alanyl-gamma-D-glutamyl-L-lysine + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine

2 entries

ATP + L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanine + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-L-lysyl-D-alanine

Psychrobacter arcticus

Q4FVQ2

-

728549

-

-

?

ATP + L-alanyl-gamma-D-glutamyl-meso-diaminopimelate + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate

2 entries

ATP + L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanine + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanine

Psychrobacter arcticus

Q4FVQ2

-

728549

-

-

?

ATP + L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanyl-D-alanine + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanyl-D-alanine

Psychrobacter arcticus

Q4FVQ2

-

728549

-

-

?

additional information

?

-

3 entries

ATP + L-alanine + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine

Psychrobacter arcticus

Q4FVQ2

-

728549

-

-

?

ATP + L-alanine + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine

Psychrobacter arcticus 273-4

Q4FVQ2

-

728549

-

-

?

ATP + L-alanyl-gamma-D-glutamate + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamate

Psychrobacter arcticus

Q4FVQ2

-

728549

-

-

?

ATP + L-alanyl-gamma-D-glutamate + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamate

Psychrobacter arcticus 273-4

Q4FVQ2

-

728549

-

-

?

ATP + L-alanyl-gamma-D-glutamyl-L-lysine + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine

Psychrobacter arcticus

Q4FVQ2

-

728549

-

-

?

ATP + L-alanyl-gamma-D-glutamyl-L-lysine + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine

Psychrobacter arcticus 273-4

Q4FVQ2

-

728549

-

-

?

ATP + L-alanyl-gamma-D-glutamyl-meso-diaminopimelate + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate

Psychrobacter arcticus

Q4FVQ2

-

728549

-

-

?

ATP + L-alanyl-gamma-D-glutamyl-meso-diaminopimelate + UDP-MurNAc

ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate

Psychrobacter arcticus 273-4

Q4FVQ2

-

728549

-

-

?

additional information

?

-

Psychrobacter arcticus

Q4FVQ2

substrate specificity of Mpl, overview. No activity with L-Ala-c-D-Glu-L-Lys-D-Ala-D-Ala

728549

-

-

?

additional information

?

-

Psychrobacter arcticus 273-4

Q4FVQ2

substrate specificity of Mpl, overview. No activity with L-Ala-c-D-Glu-L-Lys-D-Ala-D-Ala

728549

-

-

?

additional information

?

-

Psychrobacter arcticus 273-4

-

substrate specificity of Mpl, overview. No activity with L-Ala-c-D-Glu-L-Lys-D-Ala-D-Ala

728549

-

-

?