6.3.2.45: UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase

This is an abbreviated version, for detailed information about UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase, go to the full flat file.

Reaction

ATP
+
UDP-N-acetyl-alpha-D-muramate
+
L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate
=
ADP
+
phosphate
+
UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate

Synonyms

Mpl, murein peptide ligase, UDP-MurNAc:L-Ala-gamma-D-Glu-meso-A2pm ligase, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase, UDP-N-alpha-D-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate (ADP-forming), yjfG

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.2 Acid—amino-acid ligases (peptide synthases)
                6.3.2.45 UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase