6.2.1.9: malate-CoA ligase
This is an abbreviated version!
For detailed information about malate-CoA ligase, go to the full flat file.
Word Map on EC 6.2.1.9
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6.2.1.9
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succinyl-coa
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succinate
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methylobacterium
-
phosphoenzyme
-
glyoxylate
-
methanol
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extorquens
-
carboxylase
-
feedstock
-
xylose
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enzyme-bound
- 6.2.1.9
- succinyl-coa
- succinate
-
methylobacterium
- phosphoenzyme
- glyoxylate
- methanol
-
extorquens
- carboxylase
-
feedstock
- xylose
-
enzyme-bound
Reaction
Synonyms
Malate thiokinase, Malyl coenzyme A synthetase, Malyl-CoA synthetase, MTK-alpha, MTK-beta, Synthetase, malyl coenzyme A
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Inhibitors
Inhibitors on EC 6.2.1.9 - malate-CoA ligase
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ATP
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high substrate concentrations of ATP inhibit the enzyme activity
Methoxycarbonyl-CoA disulfide
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ATP protects, low concentrations of succinyl-CoA protect, L-malate protects only in absence of added sulfate. The inhibitor produces half-of-the-sites reactivity with respect to enzyme phosphorylation