6.2.1.35: acetate-[acyl-carrier protein] ligase

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For detailed information about acetate-[acyl-carrier protein] ligase, go to the full flat file.

Reaction

Synonyms

ACP-SH:acetate ligase, HS-acyl-carrier protein:acetate ligase, S01.274, [acyl-carrier protein]:acetate ligase

ECTree

     6 Ligases

         6.2 Forming carbon-sulfur bonds

             6.2.1 Acid-thiol ligases

                6.2.1.35 acetate-[acyl-carrier protein] ligase

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6	AA Sequence
1	CAS Registry Number
1	Inhibitors
2	Organism
1	Pathway
1	Purification (Commentary)
1	Reaction
2	Reference
2	Substrates and Products (Substrate)
4	Synonyms
1	Systematic Name

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Systematic Name on EC 6.2.1.35 - acetate-[acyl-carrier protein] ligase

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SYSTEMATIC NAME

IUBMB Comments

acetate:[acyl-carrier-protein] ligase (AMP-forming)

This enzyme, from the anaerobic bacterium Malonomonas rubra, is a component of the multienzyme complex EC 7.2.4.4, biotin-dependent malonate decarboxylase. The enzyme uses the energy from hydrolysis of ATP to convert the thiol group of the acyl-carrier-protein-bound 2'-(5-phosphoribosyl)-3'-dephospho-CoA prosthetic group into its acetyl thioester [2].