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BRENDA support

5.4.99.45: tRNA pseudouridine38/39 synthase

This is an abbreviated version!
For detailed information about tRNA pseudouridine38/39 synthase, go to the full flat file.

Reaction

tRNA uridine38/39
=
tRNA pseudouridine38/39

Synonyms

Deg1, Deg1p, mPus3p, pseudouridine synthase 3, PUS3, PUS3/DEG1, Pus3p

ECTree

     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.45 tRNA pseudouridine38/39 synthase

Reference

Reference on EC 5.4.99.45 - tRNA pseudouridine38/39 synthase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lecointe, F.; Simos, G.; Sauer, A.; Hurt, E.; Motorin, Y.; Grosjean, H.
Characterization of yeast protein Deg1 as pseudouridine synthase (pus3) catalyzing the formation of psi 38 and psi 39 in tRNA anticodon loop
J. Biol. Chem.
273
1316-1323
1998
Saccharomyces cerevisiae (P31115)
Manually annotated by BRENDA team
Lecointe, F.; Namy, O.; Hatin, I.; Simos, G.; Rousset, J-P.; Grosjean, H.
Lack of pseudouridine 38/39 in the anticodon arm of yeast cytoplasmic tRNA decreases in vivo recoding efficiency
J. Biol. Chem.
277
30445-30453
2002
Saccharomyces cerevisiae (P31115)
Manually annotated by BRENDA team
Chen, J.; Patton, J.R.
Pseudouridine synthase 3 from mouse modifies the anticodon loop of tRNA
Biochemistry
39
12723-12730
2000
Mus musculus (Q9JI38)
Manually annotated by BRENDA team
Hepfer, C.E.; Arnold-Croop, S.; Fogell, H.; Steudel, K.G.; Moon, M.; Roff, A.; Zaikoski, S.; Rickman, A.; Komsisky, K.; Harbaugh, D.L.; Lang, G.I.; Keil, R.L.
DEG1, encoding the tRNA:pseudouridine synthase Pus3p, impacts HOT1-stimulated recombination in Saccharomyces cerevisiae
Mol. Genet. Genomics
274
528-538
2005
Saccharomyces cerevisiae (P31115)
Manually annotated by BRENDA team
Klassen, R.; Schaffrath, R.
Role of pseudouridine formation by Deg1 for functionality of two glutamine isoacceptor tRNAs
Biomolecules
7
pii: E8
2017
Saccharomyces cerevisiae (P31115), Saccharomyces cerevisiae ATCC 204508 / S288c / BY4741 (P31115)
Manually annotated by BRENDA team