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Literature summary for 5.4.99.45 extracted from

  • Lecointe, F.; Simos, G.; Sauer, A.; Hurt, E.; Motorin, Y.; Grosjean, H.
    Characterization of yeast protein Deg1 as pseudouridine synthase (pus3) catalyzing the formation of psi 38 and psi 39 in tRNA anticodon loop (1998), J. Biol. Chem., 273, 1316-1323.
    View publication on PubMed
Search for more literature for 5.4.99.45

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Saccharomyces cerevisiae 5737
-
nucleus
-
 Saccharomyces cerevisiae 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
tRNA uridine38 Saccharomyces cerevisiae
-
 tRNA pseudouridine38
-
 ?
tRNA uridine39 Saccharomyces cerevisiae
-
 tRNA pseudouridine39
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P31115
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
tRNA uridine38
-
 Saccharomyces cerevisiae tRNA pseudouridine38
-
 ?
tRNA uridine39
-
 Saccharomyces cerevisiae tRNA pseudouridine39
-
 ?

Synonyms

Synonyms Comment Organism
Deg1p
-
 Saccharomyces cerevisiae
Pus3p
-
 Saccharomyces cerevisiae

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 activity of yeast extract and purified yeast enzyme Saccharomyces cerevisiae
37
-
 activity of Escherichia coli extract Saccharomyces cerevisiae

General Information

General Information Comment Organism
malfunction disruption of the DEG1 gene is not lethal but reduces considerably the yeast growth rate, especially at an elevated temperature, 37 °C Saccharomyces cerevisiae