5.4.99.33: cucurbitadienol synthase

This is an abbreviated version!
For detailed information about cucurbitadienol synthase, go to the full flat file.

Word Map on EC 5.4.99.33

5.4.99.33

triterpenoids

cucurbitacins

triterpene

mogrosides

cucurbitane-type

oxidosqualene

cucurbitaceae

siraitia

2,3-oxidosqualene

grosvenorii

tetracyclic

cyclases

sweeten

bitter

lanosterol

cyclization

glycosyltransferases

saponins

momordica

epoxidase

isoprenoid

taste

cycloartenol

cucurbitaceous

melon

charantia

Reaction

Synonyms

CBS, CcCDS2, CpCPQ, CPQ, SgCbQ

ECTree

5 Isomerases

5.4 Intramolecular transferases

5.4.99 Transferring other groups

5.4.99.33 cucurbitadienol synthase

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Results	in table
3	AA Sequence
5	Cloned(Commentary)
5	General Information
5	Natural Substrates/ Products (Substrates)
6	Organism
2	Pathway
1	pH Optimum
4	Protein Variants
1	Reaction
6	Reference
7	Source Tissue
7	Substrates and Products (Substrate)
7	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

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Reference on EC 5.4.99.33 - cucurbitadienol synthase

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716949

Shibuya, M.; Adachi, S.; Ebizuka, Y.

Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis

Tetrahedron

6995-7003

2004

Cucurbita pepo (Q6BE24)

746038

Dai, L.; Liu, C.; Zhu, Y.; Zhang, J.; Men, Y.; Zeng, Y.; Sun, Y.

Functional characterization of cucurbitadienol synthase and triterpene glycosyltransferase involved in biosynthesis of mogrosides from Siraitia grosvenorii

Plant Cell Physiol.

1172-1182

2015

Siraitia grosvenorii (K7NBZ9), Siraitia grosvenorii

25759326

746042

Zhang, J.; Dai, L.; Yang, J.; Liu, C.; Men, Y.; Zeng, Y.; Cai, Y.; Zhu, Y.; Sun, Y.

Oxidation of cucurbitadienol catalyzed by CYP87D18 in the biosynthesis of mogrosides from Siraitia grosvenorii

Plant Cell Physiol.

1000-1007

2016

Siraitia grosvenorii (K7NBZ9), Siraitia grosvenorii

26903528

749428

Davidovich-Rikanati, R.; Shalev, L.; Baranes, N.; Meir, A.; Itkin, M.; Cohen, S.; Zimbler, K.; Portnoy, V.; Ebizuka, Y.; Shibuya, M.; Burger, Y.; Katzir, N.; Schaffer, A.A.; Lewinsohn, E.; Tadmor, Y.

Recombinant yeast as a functional tool for understanding bitterness and cucurbitacin biosynthesis in watermelon (Citrullus spp.)

Yeast

103-114

2015

no activity in Citrullus lanatus var. lanatus, Citrullus colocynthis (A0A0D3QXV2), Citrullus colocynthis, Cucurbita pepo (Q6BE24)

25308777