5.4.99.29: 23S rRNA pseudouridine746 synthase

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For detailed information about 23S rRNA pseudouridine746 synthase, go to the full flat file.

Reaction

Synonyms

23S RNA PSI746 synthase, pseudouridine synthase RluA, RluA

ECTree

5 Isomerases

5.4 Intramolecular transferases

5.4.99 Transferring other groups

5.4.99.29 23S rRNA pseudouridine746 synthase

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Results	in table
630	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
1	Crystallization (Commentary)
1	General Information
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
6	Organism
2	pH Optimum
2	Protein Variants
2	Purification (Commentary)
3	Reaction
6	Reference
4	Substrates and Products (Substrate)
1	Subunits
5	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
3	Temperature Stability [°C]

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General Information on EC 5.4.99.29 - 23S rRNA pseudouridine746 synthase

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malfunction

Escherichia coli

P0AA37

the rluA deletion mutant fails to form either 23S RNA pseudouridine746 or tRNA pseudouridine32. Replacement of rluA in trans on a rescue plasmid restores both pseudouridines. There is no difference in exponential growth rate between wild-type and MG1655(rluA-) either in rich or minimal medium at 24, 37, or 42°C, but when both strains are grown together, a strong selection against the deletion strain is observed

704391