5.3.1.27: 6-phospho-3-hexuloisomerase
This is an abbreviated version!
For detailed information about 6-phospho-3-hexuloisomerase, go to the full flat file.
Word Map on EC 5.3.1.27
-
5.3.1.27
-
formaldehyde
-
monophosphate
-
ribulose
-
rump
-
methanol
-
nonmethylotrophic
-
methanolicus
-
gastri
-
feedstock
-
formaldehyde-fixing
-
one-carbon
-
synthesis
-
pentose
-
fructose-6-phosphate
-
methylotrophy
-
dissimilation
-
pyrococcus
-
hyperthermophilic
-
nad-dependent
-
corynebacterium
-
methylomonas
-
glutamicum
- 5.3.1.27
- formaldehyde
- monophosphate
- ribulose
-
rump
- methanol
-
nonmethylotrophic
- methanolicus
- gastri
-
feedstock
-
formaldehyde-fixing
-
one-carbon
- synthesis
- pentose
- fructose-6-phosphate
-
methylotrophy
-
dissimilation
- pyrococcus
-
hyperthermophilic
-
nad-dependent
-
corynebacterium
-
methylomonas
- glutamicum
Reaction
Synonyms
3-hexulose-6-phosphate isomerase, 6-phospho-3-hexuloisomerase, Hpi1, Hpsi2, HxlB, PHI, phospho-3-hexuloisomerase, YckF, [acyl-carrier protein]:acetate ligase
ECTree
Advanced search results
Engineering
Engineering on EC 5.3.1.27 - 6-phospho-3-hexuloisomerase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
additional information
-
gene disruption causes moderate sensitivity to formaldehyde
additional information
fusion gene construct of 3-hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase. The gene product of 3-hexulose-6-phosphate synthase /6-phospho-3-hexuloisomerase exhibits both activities at room temperature and catalyzes the sequential reactions more efficiently than a simple mixture of the individual enzymes. The gene product of 6-phospho-3-hexuloisomerase /3-hexulose-6-phosphate synthase fails to display any enzyme activity. Escherichia coli strains harboring the 3-hexulose-6-phosphate synthase /6-phospho-3-hexuloisomerase gene consume formaldehyde more efficiently and exhibited better growth in a formaldehyde containing medium than the host strain
additional information
-
fusion gene construct of 3-hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase. The gene product of 3-hexulose-6-phosphate synthase /6-phospho-3-hexuloisomerase exhibits both activities at room temperature and catalyzes the sequential reactions more efficiently than a simple mixture of the individual enzymes. The gene product of 6-phospho-3-hexuloisomerase /3-hexulose-6-phosphate synthase fails to display any enzyme activity. Escherichia coli strains harboring the 3-hexulose-6-phosphate synthase /6-phospho-3-hexuloisomerase gene consume formaldehyde more efficiently and exhibited better growth in a formaldehyde containing medium than the host strain
-
additional information
expression of the full-length gene encoding the hybrid enzyme 3-hexulose 6-phosphate synthase/6-phospho-3-hexuloisomerase, the sequence corresponding to the 3-hexulose 6-phosphate synthase region, and the sequence corresponding to the 6-phospho-3-hexuloisomerase region produces active enzymes in Escherichia coli. The bifunctional enzyme catalyzes the sequential reaction much more efficiently than a mixture of the isolated domains
additional information
-
expression of the full-length gene encoding the hybrid enzyme 3-hexulose 6-phosphate synthase/6-phospho-3-hexuloisomerase, the sequence corresponding to the 3-hexulose 6-phosphate synthase region, and the sequence corresponding to the 6-phospho-3-hexuloisomerase region produces active enzymes in Escherichia coli. The bifunctional enzyme catalyzes the sequential reaction much more efficiently than a mixture of the isolated domains
additional information
-
deletion of bifunctional 3-hexulose-6-phosphate synthase /6-phospho-3-hexuloisomerase results in loss of growth in minimal medium, which can be recovered by addition of nucleosides to the medium