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5.3.1.13: arabinose-5-phosphate isomerase

This is an abbreviated version!
For detailed information about arabinose-5-phosphate isomerase, go to the full flat file.

Word Map on EC 5.3.1.13

Reaction

D-arabinose 5-phosphate
=
D-ribulose 5-phosphate

Synonyms

A5P isomerase, A5PI, API, arabinose 5-phosphate isomerase, Arabinose phosphate isomerase, Arabinose phosphate isomerase, arabinose phosphate, arabinose-5-phosphate isomerase, BF9343_0136, c3406 protein, D-Arabinose 5-phosphate isomerase, D-arabinose-5-phosphate isomerase, D-arabinose-5-phosphate ketol-isomerase, D-arabinose-5P isomerase, G-API, GutQ, Isomerase, arabinose phosphate, K-API, KdsD, KpsF, KPSF protein, L-API, Phosphoarabinoisomerase, YrbH

ECTree

     5 Isomerases
         5.3 Intramolecular oxidoreductases
             5.3.1 Interconverting aldoses and ketoses, and related compounds
                5.3.1.13 arabinose-5-phosphate isomerase

Crystallization

Crystallization on EC 5.3.1.13 - arabinose-5-phosphate isomerase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
to 1.7 A resolution, a tetramer of a single-domain sugar isomerase with an endogenous ligand, cytidine 5'-monophosphate-3-deoxy-D-mannooct-2-ulosonate, bound at the active site. Cytidine 5'-monophosphate-3-deoxy-D-mannooct-2-ulosonate corresponds to the end product in the 3-deoxy-D-mannooct-2-ulosonate biosynthetic pathway and presumably acts as a feedback inhibitor
mutant enzyme K59A, sitting drop vapor diffusion method, using 20% PEG 8K and 0.1 M HEPES, pH 7.5