5.3.1.13: arabinose-5-phosphate isomerase

This is an abbreviated version!
For detailed information about arabinose-5-phosphate isomerase, go to the full flat file.

Word Map on EC 5.3.1.13

5.3.1.13

kdo

3-deoxy-d-manno-octulosonate

lipopolysaccharide

lps

d-ribulose

isomerization

isomerases

d-ribulose-5-phosphate

cmp-kdo

beta-synthase

mime

cystathionine

8-phosphate

uropathogenic

enediol

3-deoxy-d-manno-oct-2-ulosonic

d-glucitol

single-domain

fragilis

k-antigen

Reaction

Synonyms

A5P isomerase, A5PI, API, arabinose 5-phosphate isomerase, Arabinose phosphate isomerase, Arabinose phosphate isomerase, arabinose phosphate, arabinose-5-phosphate isomerase, BF9343_0136, c3406 protein, D-Arabinose 5-phosphate isomerase, D-arabinose-5-phosphate isomerase, D-arabinose-5-phosphate ketol-isomerase, D-arabinose-5P isomerase, G-API, GutQ, Isomerase, arabinose phosphate, K-API, KdsD, KpsF, KPSF protein, L-API, Phosphoarabinoisomerase, YrbH

ECTree

5 Isomerases

5.3 Intramolecular oxidoreductases

5.3.1 Interconverting aldoses and ketoses, and related compounds

5.3.1.13 arabinose-5-phosphate isomerase

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Results	in table
4	Activating Compound
10589	AA Sequence
1	CAS Registry Number
14	Cloned(Commentary)
2	Crystallization (Commentary)
9	General Information
5	IC50 Value
41	Inhibitors
6	kcat/KM [mM/s]
5	Ki Value [mM]
26	KM Value [mM]
16	Metals/Ions
17	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
39	Organism
6	Pathway
6	PDB ID
15	pH Optimum
5	pH Range
6	Protein Variants
14	Purification (Commentary)
2	Reaction
7	Reaction Type
29	Reference
7	Specific Activity [micromol/min/mg]
2	Storage Stability
57	Substrates and Products (Substrate)
20	Subunits
53	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
13	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 5.3.1.13 - arabinose-5-phosphate isomerase

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(2R,3R)-2,3-dihydroxy-4-(hydroxyamino)-4-oxobutyl phosphate

Francisella tularensis

714430

(2R,3R)-4-amino-2,3-dihydroxy-4-oxobutyl phosphate

Francisella tularensis

714430

(2S,3R)-2,3-bis(acetyloxy)-4-(hydroxyamino)-4-oxobutyl phosphate

Francisella tularensis

Cd2+

Co2+

Cu2+

cytidine 5'-monophospho-3-deoxy-D-manno-2-octulosonic acid

Bacteroides fragilis

Q5LIW1

final product of the 3-deoxy-D-manno-2-octulosonic acid biosynthesis pathway

748087

EDTA

Escherichia coli

652445

Erythronic acid 4-phosphate

Escherichia coli

best inhibitor

2625

heavy metal ions

Acidipropionibacterium acidipropionici

Hg2+

Mn2+

Ni2+

oxido(dioxo)[(2R,3R)-N,2,3-trihydroxy-4-(hydroxy-kO)butanamidato]phosphate(2-)

Francisella tularensis

714430

p-hydroxymercuribenzoate

2 entries

PCMB

Acidipropionibacterium acidipropionici

2622, 2623

Phosphorylated sugars

Escherichia coli

in a series of nonphosphorylated sugars, the order of decreasing inhibitory activity is as follows: aldonic acids, alditols, aldoses

2625

Zn2+

8 entries

[(2R,3R)-1-(hydroxy-kO)-4-(hydroxyamino)-4-oxobutane-2,3-diyl diacetatato](oxido)dioxophosphate(2-)

Francisella tularensis

714430

[(2R,3R)-2,3-dihydroxy-4-(hydroxy-kO)butanamidato](oxido)dioxophosphate(2-)

Francisella tularensis

714430

[(4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl phosphate

Francisella tularensis

714430

[(4R,5R)-N-hydroxy-5-[(hydroxy-kO)methyl]-2,2-dimethyl-1,3-dioxolane-4-carboxamidato](oxido)dioxophosphate(2-)

Francisella tularensis

714430