5.1.3.24: N-acetylneuraminate epimerase
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For detailed information about N-acetylneuraminate epimerase, go to the full flat file.
Reaction
Synonyms
N-acetylneuraminate mutarotase, sialic acid epimerase, YjhT
ECTree
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Systematic Name
Systematic Name on EC 5.1.3.24 - N-acetylneuraminate epimerase
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N-acetyl-alpha-neuraminate 2-epimerase
Sialoglycoconjugates present in vertebrates are linked exclusively by alpha-linkages and are released in alpha form during degradation. This enzyme accelerates maturotation to the beta form via the open form (which also occurs as a slow spontaneous reaction). The open form is necessary for further metabolism by the bacteria.