4.2.3.6: trichodiene synthase
This is an abbreviated version!
For detailed information about trichodiene synthase, go to the full flat file.
Word Map on EC 4.2.3.6
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4.2.3.6
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trichothecene
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mycotoxin
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graminearum
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sesquiterpene
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sporotrichioides
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deoxynivalenol
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trichothecene-producing
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culmorum
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gibberella
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trichodermin
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carbocation
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stachybotrys
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chartarum
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pulicaris
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5-epi-aristolochene
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bisabolyl
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biotechnology
- 4.2.3.6
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trichothecene
-
mycotoxin
- graminearum
-
sesquiterpene
- sporotrichioides
-
deoxynivalenol
-
trichothecene-producing
- culmorum
- gibberella
-
trichodermin
-
carbocation
- stachybotrys
- chartarum
- pulicaris
- 5-epi-aristolochene
-
bisabolyl
- biotechnology
Reaction
Synonyms
EC 4.1.99.6, sesquiterpene cyclase, synthase, trichodiene, TDN synthase, trans,trans-farnesyl-diphosphate sesquiterpenoid-lyase, tri5, trichodiene synthase, trichodiene synthetase
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General Information
General Information on EC 4.2.3.6 - trichodiene synthase
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physiological function
tri5 overexpression leads to an increased production of trichodermin and tyrosol. Of these, only trichodermin has antifungal activity against Saccharomyces cerevisiae, Kluyveromyces marxianus, Candida albicans, Candida glabrata, Candida tropicalis and Aspergillus fumigatus
physiological function
expression of enzyme gene tri5 in the biocontrol strain Trichoderma harzianum CECT 2413 results in production of trichodiene in parallel with a reduction of ergosterol biosynthesis and an increase in the level of squalene. Transformants expressing tri5 display low chitinase activity and induced expression of Botrytis cinerea BOT genes, although their total antagonistic potential against phytopathogenic fungi is not reduced. Volatile organic compounds released by the tri5-transformant induce expression of tomato defence genes related to salicylic acid, and trichodiene itself strongly induces the expression of salicylic acid-responsive genes and reduces the development of lateral roots
physiological function
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tri5 overexpression leads to an increased production of trichodermin and tyrosol. Of these, only trichodermin has antifungal activity against Saccharomyces cerevisiae, Kluyveromyces marxianus, Candida albicans, Candida glabrata, Candida tropicalis and Aspergillus fumigatus
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