4.2.3.51: beta-phellandrene synthase (neryl-diphosphate-cyclizing)

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For detailed information about beta-phellandrene synthase (neryl-diphosphate-cyclizing), go to the full flat file.

Reaction

Synonyms

(E)-beta-phellandrene synthase, beta-phellandrene synthase, beta-PHLS, monoterpene synthase PHS1, phellandrene synthase 1, PHLS, PHS1, TPS20

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.3 Acting on phosphates

                4.2.3.51 beta-phellandrene synthase (neryl-diphosphate-cyclizing)

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Results	in table
1	AA Sequence
1	Application
4	Cloned(Commentary)
1	Expression
1	General Information
1	kcat/KM [mM/s]
1	KM Value [mM]
2	Localization
5	Natural Substrates/ Products (Substrates)
6	Organism
1	Pathway
1	Reaction
6	Reference
2	Source Tissue
7	Substrates and Products (Substrate)
12	Synonyms
1	Systematic Name
1	Turnover Number [1/s]

General Information

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General Information on EC 4.2.3.51 - beta-phellandrene synthase (neryl-diphosphate-cyclizing)

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GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

physiological function

Solanum lycopersicum

C1K5M3

transgenic fruits overexpressing isoform PHS1 produce only small amounts of GPP-derived monoterpene products. Neryl diphosphate synthase NDPS1 coexpression with PHS1 results in a monoterpene blend, including beta-phellandrene, similar to that produced from NPP by PHS1 in vitro and in trichomes. Fruits coexpressing both PHS1 and NDPS1 show recovery of lycopene levels compared to NDPS1 fruits. In vitro assays demonstrate that NPP serves as an inhibitor of geranylgeranyl diphosphate synthase. Monoterpenes produced in fruits coexpressing both PHS1 and NDPS1 contribute to direct plant defense negatively affecting feeding behavior of the herbivore Helicoverpa zea and displaying antifungal activity against Botrytis cinerea

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