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4.2.3.130: tetraprenyl-beta-curcumene synthase

This is an abbreviated version!
For detailed information about tetraprenyl-beta-curcumene synthase, go to the full flat file.

Reaction

all-trans-heptaprenyl diphosphate
=
tetraprenyl-beta-curcumene
+
diphosphate

Synonyms

Bcl-TS, BmeTC, More, sesterterpene/triterpene/sesquarterpene synthase, tetraprenyl-beta-curcumene cyclase, ytpB

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.130 tetraprenyl-beta-curcumene synthase

General Information

General Information on EC 4.2.3.130 - tetraprenyl-beta-curcumene synthase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
-
GFPP and HexPP, the enzyme Bcl-TS substrates, are biosynthesized by enzymes E-IDS2-S/L in Bacillus clausii, and the tetraprenyl-beta-curcumene cyclase forms baciterpenol A from tetraprenyl-beta-curcumene. Proposed pathways for the biosynthesis of acyclic terpenes and menaquinones by Bacillus clausii, overview
physiological function
-
the tetraprenyl-beta-curcumene synthase homologue from Bacillus clausii (Bcl-TS) catalyzes the conversion of (all-E)-geranylfarnesyl diphosphate (GFPP) and (all-E)-hexaprenyl diphosphate (HexPP) into beta-geranylfarnesene and beta-hexaprene, respectively, in vitro, and both compounds are produced in Bacillus clausii. THe enzyme is involved in the biosynthesis of menaquinones
additional information