Information on EC 4.2.3.130 - tetraprenyl-beta-curcumene synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Mark a special word or phrase in this record:
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)


The expected taxonomic range for this enzyme is: Bacillus

EC NUMBER
COMMENTARY
4.2.3.130
-
RECOMMENDED NAME
GeneOntology No.
tetraprenyl-beta-curcumene synthase
-
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
all-trans-heptaprenyl diphosphate = tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
all-trans-heptaprenyl-diphosphate diphosphate-lyase (cyclizing, tetraprenyl-beta-curcumene-forming)
Isolated from Bacillus subtilis. This sesquarterpene is present in a number of Bacillus species.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
ytpB
-
-
gene name
-
ytpB
-
gene name
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
gene ytpB
UniProt
Manually annotated by BRENDA team
gene Bcell_3320
UniProt
Manually annotated by BRENDA team
gene BMD_4842
UniProt
Manually annotated by BRENDA team
gene ytpB
UniProt
Manually annotated by BRENDA team
Bacillus megaterium 168
gene ytpB
UniProt
Manually annotated by BRENDA team
Bacillus megaterium 319
gene BMD_4842
UniProt
Manually annotated by BRENDA team
gene ytpB
UniProt
Manually annotated by BRENDA team
gene ytpB or ts
-
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
additional information
-
the ts gene or ytpB gene forms an operon with a lysophospholipase gene ytpA, which is responsible for the biosynthesis of the antibiotic bacilysocin in Bacillus subtilis
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
-
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
D5DN48, O34707
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
E1UNG0
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
E3E331
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
E6U1R5
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
A8FGH3
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
-
-
tetraprenyl-beta-curcumene shows nonenzymatic autooxidation to tetraprenyl-alpha-curcumene
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
Bacillus megaterium 319
D5DN48
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
E3E331
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
Bacillus megaterium 168
O34707
-
-
-
?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
-
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
D5DN48, O34707
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
E1UNG0
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
E3E331
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
E6U1R5
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
A8FGH3
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
Bacillus megaterium 319
D5DN48
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
E3E331
-
-
-
?
all-trans-heptaprenyl diphosphate
tetraprenyl-beta-curcumene + diphosphate
show the reaction diagram
Bacillus megaterium 168
O34707
-
-
-
?
Purification/COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
recombinant fusion protein YtpB from Escherichia coli strain BL21(DE3) by affinity chromatography
-
Cloned/COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
gene ytpB, expression as fusion protein in Escherichia coli strain BL21(DE3) from pColdTF. The ts gene or ytpB gene forms an operon with a lysophospholipase gene ytpA, which is responsible for the biosynthesis of the antibiotic bacilysocin in Bacillus subtilis
-