4.2.2.15: anhydrosialidase

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For detailed information about anhydrosialidase, go to the full flat file.

Reaction

Synonyms

alpha-(2,3)-specific trans-salidase, anhydroneuraminidase, EC 3.2.1.138, NanB, neuraminidase B, neuraminidase, anhydro-, sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing), sialidase L

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.2 Acting on polysaccharides

                4.2.2.15 anhydrosialidase

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Results	in table
4	AA Sequence
1	Application
1	CAS Registry Number
2	Cloned(Commentary)
2	Crystallization (Commentary)
1	General Stability
1	Inhibitors
1	KM Value [mM]
1	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
5	Organism
1	PDB ID
1	pH Optimum
1	pI Value
2	Purification (Commentary)
1	Reaction
1	Reaction Type
5	Reference
1	Specific Activity [micromol/min/mg]
1	Storage Stability
8	Substrates and Products (Substrate)
2	Subunits
8	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Crystallization

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Crystallization on EC 4.2.2.15 - anhydrosialidase

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CRYSTALLIZATION (Commentary)

ORGANISM

UNIPROT

LITERATURE

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Macrobdella decora

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648544

crystal structure of NanB in complex with its reaction product 2,7-anhydro-Neu5Ac is reported. NanB crystal structure consists of an N-terminal lectin-like domain (L-domain, residues 30-227), a catalytic six-bladed beta-propeller domain (N-domain, residues 228-345 and 457-697), and an irregular beta-stranded domain inserted into the catalytic domain (I-domain, residues 346-456)

Streptococcus pneumoniae

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692359