4.2.1.70: pseudouridylate synthase

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For detailed information about pseudouridylate synthase, go to the full flat file.

Reaction

Synonyms

16S pseudouridine 516 synthase, 16S pseudouridylate 516 synthase, 5-ribosyluracil 5'-phosphate synthetase, Depressed growth-RATE protein DEG1, IndA, More, ORP protein, Osmoprotectant regulator of PLC, P35 protein, pseudouridine monophosphate synthetase, pseudouridine synthase, pseudouridine synthase I, pseudouridine-5'-phosphate glycosidase, Pseudouridylate synthase, pseudouridylate synthetase, pseudouridylate synthetase I, pseudouridylate synthetase II, pseudouridylic acid synthetase, PSI55 synthase, psi55 tRNA pseudouridine synthase, psiMP synthetase, psisynthetase, psiUMP synthetase, PSUI, PUS, synthase, pseudouridylate, tRNA pseudouridine 55 synthase, TruB, uracil hydrolyase, YeiN

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.1 Hydro-lyases

                4.2.1.70 pseudouridylate synthase

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Results	in table
9218	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
2	Crystallization (Commentary)
2	General Information
4	General Stability
10	Inhibitors
1	Ki Value [mM]
9	KM Value [mM]
2	Localization
6	Metals/Ions
5	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
107	Organism
3	Pathway
37	PDB ID
5	pH Optimum
2	pH Range
9	Purification (Commentary)
1	Reaction
40	Reaction Type
72	Reference
2	Source Tissue
15	Specific Activity [micromol/min/mg]
2	Storage Stability
64	Substrates and Products (Substrate)
3	Subunits
41	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
2	Temperature Range [°C]
1	Temperature Stability [°C]
3	Turnover Number [1/s]

pH Range

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pH Range on EC 4.2.1.70 - pseudouridylate synthase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

7 - 9.5

Agrobacterium tumefaciens

-

pH 7.0 about 50% of maximal activity, pH 9.5 about 80% of maximal activity

5840

7.5 - 10

Nicotiana glauca

-

pH 7.5 about 40% of maximal activity, pH 10 about 20% of maximal activity

5843