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4.2.1.148: 2-methylfumaryl-CoA hydratase

This is an abbreviated version!
For detailed information about 2-methylfumaryl-CoA hydratase, go to the full flat file.

Word Map on EC 4.2.1.148

Reaction

(2R,3S)-2-methylmalyl-CoA
=
2-methylfumaryl-CoA
+
H2O

Synonyms

erythro-beta-methylmalonyl-CoA hydrolyase, Hah_1340, MCD, Mch, mesaconyl-C1-CoA hydratase, mesaconyl-CoA hydratase, mesaconyl-coenzyme A hydratase, More

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.148 2-methylfumaryl-CoA hydratase

Inhibitors

Inhibitors on EC 4.2.1.148 - 2-methylfumaryl-CoA hydratase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
CaCl2
18% inhibition at 5 mM; 5 mM, 18% inhibition
CoCl2
40% inhibition at 5 mM; 5 mM, 34% inhibition
MgCl2
11% inhibition at 5 mM; 5 mM, 11% inhibition
MnCl2
22% inhibition at 5 mM; 5 mM, 22% inhibition
NiCl2
34% inhibition at 5 mM; 5 mM, 40% inhibition
additional information
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