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4.2.1.148: 2-methylfumaryl-CoA hydratase

This is an abbreviated version!
For detailed information about 2-methylfumaryl-CoA hydratase, go to the full flat file.

Word Map on EC 4.2.1.148

Reaction

(2R,3S)-2-methylmalyl-CoA
=
2-methylfumaryl-CoA
+
H2O

Synonyms

erythro-beta-methylmalonyl-CoA hydrolyase, Hah_1340, MCD, Mch, mesaconyl-C1-CoA hydratase, mesaconyl-CoA hydratase, mesaconyl-coenzyme A hydratase, More

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.148 2-methylfumaryl-CoA hydratase

Substrates Products

Substrates Products on EC 4.2.1.148 - 2-methylfumaryl-CoA hydratase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2R,3S)-2-methyl-3-hydroxysuccinyl-C4-CoA + H2O
3-methylfumaryl-CoA + H2O
show the reaction diagram
i.e. (S)-citramalyl-CoA
-
-
r
(2R,3S)-2-methylmalyl-CoA
2-methylfumaryl-CoA + H2O
show the reaction diagram
(S)-citramalyl-CoA
3-methylfumaryl-CoA + H2O
show the reaction diagram
-
-
-
r
(S)-malyl-CoA
fumaryl-CoA + H2O
show the reaction diagram
-
-
-
r
2-methylfumaryl-CoA + H2O
(2R,3S)-2-methylmalyl-CoA
show the reaction diagram
3-methylfumaryl-CoA + H2O
(S)-citramalyl-CoA
show the reaction diagram
i.e. mesaconyl-C4-CoA
-
-
r
fumaryl-CoA + H2O
(S)-malyl-CoA
show the reaction diagram
-
-
-
r
mesaconyl-C1-CoA
(2R,3S)-2-methyl-3-hydroxysuccinyl-C1-CoA + H2O
show the reaction diagram
mesaconyl-C4-CoA + H2O
(2R,3S)-2-methyl-3-hydroxysuccinyl-C4-CoA + H2O
show the reaction diagram
EC 4.2.1.153
-
-
r
additional information
?
-