4.2.1.134: very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

This is an abbreviated version!
For detailed information about very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase, go to the full flat file.

Reaction

Synonyms

3 hydroxyacyl-CoA dehydratase, 3-hydroxyacyl-CoA dehydratase, EC 2.3.1.119, Fatty acid elongase, fatty acyl-CoA dehydratase, HACD1, HACD2, HACD3, HACD4, HCD, PAS2, PASTICCINO 2, PASTICCINO2, PHS1, PTPLA, PTPLA dehydratase, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase, very-long-chain hydroxy fatty acyl-CoA dehydratase

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.1 Hydro-lyases

                4.2.1.134 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

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Results	in table
7828	AA Sequence
2	Application
6	Cloned(Commentary)
52	Disease/ Diagnostics
2	Expression
20	General Information
1	Inhibitors
4	KM Value [mM]
4	Localization
4	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
11	Organism
26	Pathway
1	Posttranslational Modification
25	Protein Variants
1	Reaction
10	Reference
9	Source Tissue
7	Substrates and Products (Substrate)
4	Subunits
36	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

KM Value

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KM Value on EC 4.2.1.134 - very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0068 - 0.1217

3-hydroxypalmitoyl-CoA

4 entries

0.0068

3-hydroxypalmitoyl-CoA

Homo sapiens

-

isoform HCAD4, in 50 mM HEPES-NaOH (pH 7.4), 150 mM NaCl, 10% (v/v) glycerol, 1 mM dithiothreitol, 1 mM phenylmethylsulfonyl fluoride, at 37°C

719491

0.0336

3-hydroxypalmitoyl-CoA

Homo sapiens

-

isoform HCAD1, in 50 mM HEPES-NaOH (pH 7.4), 150 mM NaCl, 10% (v/v) glycerol, 1 mM dithiothreitol, 1 mM phenylmethylsulfonyl fluoride, at 37°C

719491

0.0495

3-hydroxypalmitoyl-CoA

Homo sapiens

-

isoform HCAD3, in 50 mM HEPES-NaOH (pH 7.4), 150 mM NaCl, 10% (v/v) glycerol, 1 mM dithiothreitol, 1 mM phenylmethylsulfonyl fluoride, at 37°C

719491

0.1217

3-hydroxypalmitoyl-CoA

Homo sapiens

-

isoform HCAD2, in 50 mM HEPES-NaOH (pH 7.4), 150 mM NaCl, 10% (v/v) glycerol, 1 mM dithiothreitol, 1 mM phenylmethylsulfonyl fluoride, at 37°C

719491