4.2.1.125: dammarenediol II synthase

This is an abbreviated version!
For detailed information about dammarenediol II synthase, go to the full flat file.

dammarenediol synthase, dammarenediol-II synthase, DDS, PgDDS, PgDDS1, PNA

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Results	in table
1	Activating Compound
2	AA Sequence
1	Application
12	Cloned(Commentary)
2	Expression
11	General Information
5	Inhibitors
4	Localization
5	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
16	Organism
5	Pathway
3	pH Optimum
18	Protein Variants
2	Purification (Commentary)
3	Reaction
16	Reference
13	Source Tissue
17	Substrates and Products (Substrate)
5	Subunits
22	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Substrates Products on EC 4.2.1.125 - dammarenediol II synthase

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(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O

dammarenediol II

(3S)-2,3-oxidosqualene + H2O

(20S)-dammarenediol

(S)-2,3-oxidosqualene + H2O

(20S)-dammarenediol

S-isomer is the sole product, water addition to the dammarenyl cation intermediate is stereospecific

(S)-2,3-oxidosqualene + H2O

(20S)-dammarenediol + hydroxydammarenone

additional information