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4.1.99.1: tryptophanase

This is an abbreviated version!
For detailed information about tryptophanase, go to the full flat file.

Word Map on EC 4.1.99.1

Reaction

L-tryptophan
+
H2O
=
indole
+
pyruvate
+
NH3

Synonyms

L-tryptophan indole-lyase, L-tryptophanase, TIL, tna2, TnaA, tnaA2, TNase, Tpase, Trpase, tryptophan indole lyase, tryptophan indole-lyase, tryptophan-indole lyase, tryptophanase, tryptophanase 2, VcTrpase

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.99 Other carbon-carbon lyases
                4.1.99.1 tryptophanase

Expression

Expression on EC 4.1.99.1 - tryptophanase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
bicarbonate stimulated transcription of gene tna2. The transcription of some genes involved in amino acid metabolism is sigma54-dependent, and a bacterial enhancer-binding protein containing a PAS domain controls the transcription under the presence of high levels of bicarbonate, coculture-dependent expression of tryptophanase in Symbiobacterium thermophilum, overview
the endogenous oxidative stress in ibpAB cells leads to increased expression of tryptophanase
-
the tryptophase operon expression is induced by L-tryptophan
-
tryptophanase activity is decreased by 43% after lactic acid bacteria treatment (300 billion CFU/g twice a day for 2 weeks)
-
tryptophanase is often overexpressed in stressed cultures, e.g. under alkaline stress
tryptophanase is upregulated in the noninvasive ibeR deletion mutant BR2