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3.5.4.B9: cytosine deaminase APOBEC3G

This is an abbreviated version!
For detailed information about cytosine deaminase APOBEC3G, go to the full flat file.

Word Map on EC 3.5.4.B9

Reaction

cytosine in single-stranded viral DNA
+
H2O
=
uracil in single-stranded viral DNA
+
NH3

Synonyms

A3G, ABOBEC3G, activation-induced deaminase, Apo3G, Apobec 3G, APOBEC3G, APOBEC3G cytidine deaminase, APOBEC3G DNA deaminase, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G, apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G, apolipoprotein B mRNA-editing, enzyme-catalytic, polypeptide-like 3G, CEM15, DNA cytidine deaminase, More, single-stranded DNA deoxycytidine deaminase, single-stranded DNA-dependent deoxycytidine deaminase, ssDNA deoxycytidine deaminase

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.4 In cyclic amidines
                3.5.4.B9 cytosine deaminase APOBEC3G

Disease

Disease on EC 3.5.4.B9 - cytosine deaminase APOBEC3G

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acquired Immunodeficiency Syndrome
Exhaustive genotyping of the CEM15 (APOBEC3G) gene and absence of association with AIDS progression in a French cohort.
Breast Neoplasms
Evidence for APOBEC3B mutagenesis in multiple human cancers.
Carcinogenesis
Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor.
Infections
APOBEC3G-independent reduction in virion infectivity during long-term HIV-1 replication in terminally differentiated macrophages.
Influenza, Human
Apobec 3F and apobec 3G have no inhibition and hypermutation effect on the human influenza A virus.
Leukemia
APOBEC3G targets specific virus species.
Neoplasms
APOBEC3B and IL-6 form a positive feedback loop in hepatocellular carcinoma cells.
Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor.